BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Motif caller for sequence reconstruction in motif-based DNA storage. [PDF]
Agarwal P, Pinnamaneni N, Heinis T.
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Gungnir codec enabling high error-tolerance and low-redundancy DNA storage through substantial computing power. [PDF]
Zhang J +8 more
europepmc +1 more source
Study of the error correction capability of multiple sequence alignment algorithm (MAFFT) in DNA storage. [PDF]
Xie R, Zan X, Chu L, Su Y, Xu P, Liu W.
europepmc +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning. [PDF]
Li X +8 more
europepmc +1 more source
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
De-Bruijn graph partitioning for scalable and accurate DNA storage processing. [PDF]
De Moor F, Boullé O, Lavenier D.
europepmc +1 more source
Correction to: DeSP: a systematic DNA storage error simulation pipeline. [PDF]
Yuan L, Xie Z, Wang Y, Wang X.
europepmc +1 more source

