Results 281 to 290 of about 698,910 (309)

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Scaling the High-YieldPotential of Large-Scale DNAData Storage with Cap-Free DNA Synthesis

Weiming Lin (13253381), Haotian Yu (8266695), Weihao Li (2390917), Yemin Han (21659806), Manman Lv (21659809), Han Gao (486886), Mengqing Cheng (8745807), Yan Huang (46805), Kun Bi (139916), Zuhong Lu (7094), Quanjun Liu (133069)   +10 more
openalex   +1 more source

Contains further methodological detail on: venom storage, DNA extraction (from venoms and skins), PCR, Sanger sequencing, antivenom reconstitution and control immunoglobulins, size exclusion chromatography, ELISA, PLA2 assay, SVMP assay, plasma clotting assay, preclinical assays.

Rebecca J. Edge (12732488), Amy E. Marriott (10519764), Molly Keen (21983146), Tiffany Xie (21983149), Edouard P. Crittenden (17677320), Charlotte A. Dawson (17632944), Mark C. Wilkinson (2202700), Wolfgang Wüster (360453), Nicholas R. Casewell (7062380), Stuart Ainsworth (4520902), Stefanie K. Menzies (9262708)   +10 more
openalex   +1 more source

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Data Storage Using DNA

Advanced Materials, 2023
AbstractThe exponential growth of global data has outpaced the storage capacities of current technologies, necessitating innovative storage strategies. DNA, as a natural medium for preserving genetic information, has emerged as a highly promising candidate for next‐generation storage medium.
Shaopeng Wang, Xiuhai Mao, Fei Wang, Xiaolei Zuo, Chunhai Fan   +4 more
openaire   +2 more sources

Novel Modalities in DNA Data Storage

Trends in Biotechnology, 2021
The field of storing information in DNA has expanded exponentially. Most common modalities involve encoding information from bits into synthesized nucleotides, storage in liquid or dry media, and decoding via sequencing. However, limitations to this paradigm include the cost of DNA synthesis and sequencing, along with low throughput. Further unresolved
Cheng Kai Lim, Saurabh Nirantar, Wen Shan Yew, Chueh Loo Poh   +3 more
openaire   +2 more sources

DNA degradation during organ storage

Experientia, 1974
Es wurden Kerne aus isolierten Mausenieren, die unter warmen und kalten Bedingungen aufbewahrt worden waren, isoliert. Nach der Bestimmung der Viskositat wurde das Molekulargewicht der kernhaltigen DNS wahrend der Konservierung reduziert. Die Abnahme der DNS-Molekulargrosse bewirkt moglicherweise eine Kurzung der Uberlebensdauer des isolierten Organs.
H M, Lazarus, A, Hopfenbeck
openaire   +2 more sources

DNA DATA STORAGE

2021
Human Beings have always tried to simplify the way of storing data maintaining both security and speed of access. This decade(2011-2020) is focusing on improving data storage devices. New technologies like SSDs (Solid State Drives), technical upgrades in SATA or IDE HDDs (Hard Disk Drives), etc with Terra Bytes of storage capabilities have come to ...
openaire   +1 more source

Data Storage in DNA

International Journal of Electrical Energy, 2014
Human-beings have always been fond of accessing more and more information in minimum possible time and space. Consequently New Generation Computers and High Speed Internet have gained popularity in the recent years. We have been witness to remarkable achievements like the transition from the bulky hard-drives to the flash drives which has made personal
Siddhant Shrivastava, Rohan Badlani
openaire   +1 more source