Results 171 to 180 of about 2,195,182 (275)

On Degradation-Induced Leak in Heterochiral DNA Strand Displacement Cascades. [PDF]

ACS Synth Biol
Mallette TL, Mishra A, Lakin MR.
europepmc   +1 more source

Direct Comparison of d-DNA and l-DNA Strand-Displacement Reactions in Living Mammalian Cells. [PDF]

ACS Synth Biol, 2021
Zhong W, Sczepanski JT.
europepmc   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

Advanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang, Narina Jung, Min‐Hyeok Kim, Wanyoung Lim, Zhenzhong Chen, Byung Mook Weon, Sungsu Park   +6 more
wiley   +1 more source

Enriching Higher Affinity Aptamers by Addressing the Kinetic Aspect of the DNA Strand-Displacement Reaction. [PDF]

Angew Chem Int Ed Engl
Ding Y, Heng Y, Wong KY, Chen Q, Liu J.
europepmc   +1 more source

Kinetics of Toehold-Mediated DNA Strand Displacement Depend on Fe^II₄L₄ Tetrahedron Concentration. [PDF]

Nano Lett, 2021
Zhu J, Bošković F, Nguyen BT, Nitschke JR, Keyser UF.   +4 more
europepmc   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Kinetic Proofreading can Enhance Specificity in a Non-enzymatic DNA Strand Displacement Network

, 2023
Mukherjee R, Sengar A, Cabello-García J, Ouldridge TE.   +3 more
europepmc   +1 more source

DNA Strand Displacement with Base Pair Stabilizers: Purine-2,6-Diamine and 8-Aza-7-Bromo-7-Deazapurine-2,6-Diamine Oligonucleotides Invade Canonical DNA and New Fluorescent Pyrene Click Sensors Monitor the Reaction. [PDF]

Chemistry, 2022
Zhang A, Kondhare D, Leonard P, Seela F.
europepmc   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Design of mismatch closure for enhanced specificity in DNA strand displacement reactions. [PDF]

Nucleic Acids Res
Yu H, Han X, Zhang L, Yin N, Wang L, Lv K, Wu Y, Bai D, Wang W, Huang Y, Hu X, Weng Z, Zhang C, Yang G, Chen T, Xie G.   +15 more
europepmc   +1 more source