Results 1 to 10 of about 812,407 (248)
Single-molecule force spectroscopy of toehold-mediated strand displacement [PDF]
Nature CommunicationsToehold-mediated strand displacement (TMSD) is extensively utilized in dynamic DNA nanotechnology and for a wide range of DNA or RNA-based reaction circuits.
Andreas Walbrun +5 more
doaj +2 more sources
Heterochiral DNA Strand-Displacement Based on Chimeric d/l-Oligonucleotides
, 2019 Heterochiral DNA strand-displacement reactions enable sequence-specific interfacing of oligonucleotide enantiomers, making it possible to interface native d-nucleic acids with molecular circuits built using nuclease-resistant l-DNA.
Jonathan T. Sczepanski (2035963) +3 more
core +1 more source
Strand Displacement Activity of PrimPol
, 2020 Human PrimPol is a unique enzyme possessing DNA/RNA primase and DNA polymerase activities. In this work, we demonstrated that PrimPol efficiently fills a 5-nt gap and possesses the conditional strand displacement activity stimulated by Mn2+ ions and ...
Ekaterina A. Maltseva +6 more
core +1 more source
Modular DNA strand-displacement controllers for directing material expansion
Nature Communications, 2018 Materials which change shape in response to a trigger are of interest for soft robotics and targeted therapeutic delivery. Here, the authors report on the development of DNA-crosslinked hydrogels which can expand upon the detection of different ...
Joshua Fern, Rebecca Schulman
doaj +1 more source
In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication. [PDF]
PLoS Genetics, 2014 Mitochondrial DNA (mtDNA) encodes for proteins required for oxidative phosphorylation, and mutations affecting the genome have been linked to a number of diseases as well as the natural ageing process in mammals.
Javier Miralles Fusté +8 more
doaj +1 more source
, 2022 Oligonucleotide sequences of LAMP primers and target induced-DNA strand displacement probes used in this study.
Thanyarat Chaibun (5348540) +6 more
core +1 more source
The Seismic Record, 2022 The Great Valley fault system defines the tectonic boundary between the Coast Ranges and the Central Valley in California, is active throughout the Quaternary, and has been the source of several significant (M > 6) historic earthquakes, including the ...
Charles C. Trexler +4 more
doaj +1 more source
Imaging mRNA Expression in Live Cells via PNA·DNA Strand Displacement-Activated Probes
Journal of Nucleic Acids, 2012 Probes for monitoring mRNA expression in vivo are of great interest for the study of biological and biomedical problems, but progress has been hampered by poor signal to noise and effective means for delivering the probes into live cells.
Zhenghui Wang +3 more
doaj +1 more source
, 2018 Heavy metal ions are persistent environmental contaminants and pose a great threat to human health, which has prompted demand for new methods to selectively identify and detect these metal ions. Herein, a novel fluorescent assay based on a rolling-circle-
Ruo Yuan (1405666) +6 more
core +1 more source
Nucleic Acid Strand Displacement with Synthetic mRNA Inputs in Living Mammalian Cells
, 2018 Strand displacement reactions are widely used in DNA nanotechnology as a building block for engineering molecular computers and machines. Here, we demonstrate that strand displacement-based probes can be triggered by RNA expressed in mammalian cells ...
Georg Seelig +5 more
core +2 more sources