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An Operational DNA Strand Displacement Encryption Approach [PDF]
Nanomaterials, 2022 DeoxyriboNucleic Acid (DNA) encryption is a new encryption method that appeared along with the research of DNA nanotechnology in recent years. Due to the complexity of biology in DNA nanotechnology, DNA encryption brings in an additional difficulty in ...
Enqiang Zhu +3 more
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Two-Domain DNA Strand Displacement [PDF]
Electronic Proceedings in Theoretical Computer Science, 2010 We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand.
Luca Cardelli
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Timed Pulses in DNA Strand Displacement Reactions. [PDF]
J Am Chem Soc, 2023 Inspired by naturally occurring regulatory mechanisms that allow complex temporal pulse features with programmable delays in gene expression and biological pathways, we demonstrate here a strategy to achieve temporally programmed pulse output signals in DNA-based Strand Displacement Reactions (SDRs).
Bucci J +4 more
europepmc +4 more sources
Kinetics and Activation Strategies in Toehold-Mediated and Toehold-Free DNA Strand Displacement [PDF]
BiosensorsNucleic acid strand displacement reactions (SDRs) are fundamental building blocks of dynamic DNA nanotechnology. A detailed understanding of their kinetics is crucial for designing efficient sequences and regulating reaction networks with applications in
Yuqin Wu +4 more
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Strand Displacement Activity of PrimPol [PDF]
International Journal of Molecular Sciences, 2020 Human PrimPol is a unique enzyme possessing DNA/RNA primase and DNA polymerase activities. In this work, we demonstrated that PrimPol efficiently fills a 5-nt gap and possesses the conditional strand displacement activity stimulated by Mn2+ ions and accessory replicative proteins RPA and PolDIP2. The DNA displacement activity of PrimPol was found to be
Olga Lavrik +2 more
exaly +3 more sources
Nucleic acid strand displacement – from DNA nanotechnology to translational regulation [PDF]
RNA Biology, 2023 Nucleic acid strand displacement reactions involve the competition of two or more DNA or RNA strands of similar sequence for binding to a complementary strand, and facilitate the isothermal replacement of an incumbent strand by an invader.
Friedrich C. Simmel
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Directing Uphill Strand Displacement with an Engineered Superhelicase. [PDF]
ACS Synth Biol, 2023 The ability to finely tune reaction rates and binding energies between components has made DNA strand displacement circuits promising candidates to replicate the complex regulatory functions of biological reaction networks. However, these circuits often lack crucial properties, such as signal turnover and the ability to transiently respond to ...
Hall-Thomsen H +5 more
europepmc +3 more sources
DNA strand displacement based computational systems and their applications [PDF]
Frontiers in Genetics, 2023 DNA computing has become the focus of computing research due to its excellent parallel processing capability, data storage capacity, and low energy consumption characteristics.
Congzhou Chen +4 more
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Three-input logic gate based on DNA strand displacement reaction [PDF]
Scientific Reports, 2023 In this paper, three kinds of three-input logic gates are designed based on DNA strand displacement reaction, which are three-input OR logic gate, three-input AND logic gate, and three-input MAJORITY logic gate.
M. A. Jingjing
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Structural basis for intrinsic strand displacement activity of mitochondrial DNA polymerase [PDF]
Nature CommunicationsMembers of the Pol A family of DNA polymerases, found across all domains of life, utilize various strategies for DNA strand separation during replication.
Ashok R. Nayak +5 more
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