Results 31 to 40 of about 44,419 (247)

DNA dynamics and computation based on toehold-free strand displacement

open access: yesNature Communications, 2021
Synthetic DNA constructs can to used to recognise and respond to input signals. Here the authors present complex DNA nanostructures with toehold-free strand displacement for generation of ON/OFF switches and Boolean gates.
Hong Kang   +5 more
doaj   +1 more source

Four-Input Multi-Layer Majority Logic Circuit Based on DNA Strand Displacement Computing

open access: yesIEEE Access, 2020
Biomolecules have the advantage of high performance parallel computing and large information capacity. The use of biochemical circuits to solve computational problems has been studied by many researchers.
Yanfeng Wang, Guodong Yuan, Junwei Sun
doaj   +1 more source

Leakless DNA Strand Displacement Systems [PDF]

open access: yes, 2015
While current experimental demonstrations have been limited to small computational tasks, DNA strand displacement systems DSD systemsi¾?[25] hold promise for sophisticated information processing within chemical or biological environments. A DSD system encodes designed reactions that are facilitated by three-way or four-way toehold-mediated strand ...
Chris Thachuk   +2 more
openaire   +2 more sources

DNA strand displacement, strand annealing and strand swapping by the Drosophila Bloom's syndrome helicase [PDF]

open access: yesNucleic Acids Research, 2007
Genetic analysis of the Drosophila Bloom's syndrome helicase homolog (mus309/DmBLM) indicates that DmBLM is required for the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination. Here we report the first biochemical study of DmBLM.
Weinert, Brian T, Rio, Donald C
openaire   +4 more sources

The Effect of Basepair Mismatch on DNA Strand Displacement [PDF]

open access: yesBiophysical Journal, 2016
DNA strand displacement is a key reaction in DNA homologous recombination and DNA mismatch repair and is also heavily utilized in DNA-based computation and locomotion. Despite its ubiquity in science and engineering, sequence-dependent effects of displacement kinetics have not been extensively characterized.
Broadwater, Bo, Kim, Harold
openaire   +3 more sources

Novel Viral DNA Polymerases From Metagenomes Suggest Genomic Sources of Strand-Displacing Biochemical Phenotypes

open access: yesFrontiers in Microbiology, 2022
Viruses are the most abundant and diverse biological entities on the planet and constitute a significant proportion of Earth’s genetic diversity. Most of this diversity is not represented by isolated viral-host systems and has only been observed through ...
Rachel A. Keown   +10 more
doaj   +1 more source

Coupling RNA annealing and strand displacement: a FRET-based microplate reader assay for RNA chaperone activity

open access: yesBioTechniques, 2007
Proteins with RNA chaperone activity help RNAs to obtain their native conformations, and many of them are active in the two basic reactions—RNA annealing and strand displacement.
Lukas Rajkowitsch, Renée Schroeder
doaj   +1 more source

Controlled Release in Hydrogels Using DNA Nanotechnology

open access: yesBiomedicines, 2022
Gelatin is a biopolymer widely used to synthesize hydrogels for biomedical applications, such as tissue engineering and bioinks for 3D bioprinting. However, as with other biopolymer-based hydrogels, gelatin-hydrogels do not allow precise temporal control
Chih-Hsiang Hu, Remi Veneziano
doaj   +1 more source

Construction of Multiple Logic Circuits Based on Allosteric DNAzymes

open access: yesBiomolecules, 2022
In DNA computing, the implementation of complex and stable logic operations in a universal system is a critical challenge. It is necessary to develop a system with complex logic functions based on a simple mechanism.
Xin Liu   +5 more
doaj   +1 more source

Evidence of Active Quaternary Deformation on the Great Valley Fault System near Winters, Northern California

open access: yesThe Seismic Record, 2022
The Great Valley fault system defines the tectonic boundary between the Coast Ranges and the Central Valley in California, is active throughout the Quaternary, and has been the source of several significant (M > 6) historic earthquakes, including the ...
Charles C. Trexler   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy