Results 31 to 40 of about 44,186 (249)
Double Synchronization Based on DNA Strand Displacement Reaction
IEEE Access, 2020 As an important part of biological computing, DNA strand displacement technology is used to construct complex biochemical circuits. Reversible molecular chemical reactions are basic chemical reactions.
Junwei Sun +3 more
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A novel bio-sensor based on DNA strand displacement. [PDF]
PLoS ONE, 2014 DNA strand displacement technology performs well in sensing and programming DNA segments. In this work, we construct DNA molecular systems based on DNA strand displacement performing computation of logic gates.
Xiaolong Shi +5 more
doaj +1 more source
BMC Molecular and Cell Biology, 2019 Background The discovery of thermostable DNA polymerases such as Taq DNA polymerase revolutionized amplification of DNA by polymerase chain reaction methods that rely on thermal cycling for strand separation.
Yvonne Piotrowski +2 more
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Cotranscriptionally encoded RNA strand displacement circuits. [PDF]
Sci Adv, 2022 Engineered molecular circuits that process information in biological systems could address emerging human health and biomanufacturing needs. However, such circuits can be difficult to rationally design and scale. DNA-based strand displacement reactions have demonstrated the largest and most computationally powerful molecular circuits to date but are ...
Schaffter SW, Strychalski EA.
europepmc +3 more sources
A Novel Computational Method to Reduce Leaky Reaction in DNA Strand Displacement
Journal of Analytical Methods in Chemistry, 2015 DNA strand displacement technique is widely used in DNA programming, DNA biosensors, and gene analysis. In DNA strand displacement, leaky reactions can cause DNA signals decay and detecting DNA signals fails.
Xin Li +5 more
doaj +1 more source
DNA strand displacement, strand annealing and strand swapping by the Drosophila Bloom's syndrome helicase [PDF]
Nucleic Acids Research, 2007 Genetic analysis of the Drosophila Bloom's syndrome helicase homolog (mus309/DmBLM) indicates that DmBLM is required for the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination. Here we report the first biochemical study of DmBLM.
Weinert, Brian T, Rio, Donald C
openaire +4 more sources
Leakless DNA Strand Displacement Systems [PDF]
, 2015 While current experimental demonstrations have been limited to small computational tasks, DNA strand displacement systems DSD systemsi¾?[25] hold promise for sophisticated information processing within chemical or biological environments. A DSD system encodes designed reactions that are facilitated by three-way or four-way toehold-mediated strand ...
Chris Thachuk +2 more
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The Effect of Basepair Mismatch on DNA Strand Displacement [PDF]
Biophysical Journal, 2016 DNA strand displacement is a key reaction in DNA homologous recombination and DNA mismatch repair and is also heavily utilized in DNA-based computation and locomotion. Despite its ubiquity in science and engineering, sequence-dependent effects of displacement kinetics have not been extensively characterized.
Broadwater, Bo, Kim, Harold
openaire +3 more sources
Single-molecule dilution and multiple displacement amplification for molecular haplotyping
BioTechniques, 2005 Separate haploid analysis is frequently required for heterozygous genotyping to resolve phase ambiguity or confirm allelic sequence. We demonstrate a technique of single-molecule dilution followed by multiple strand displacement amplification to ...
Philip Paul, Josh Apgar
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Molecular Full Adder Based on DNA Strand Displacement
IEEE Access, 2020 A new method, namely DNA strand displacement (DSD), has recently emerged in the field of biocomputing. DSD uses the toehold domain as a starting point to cover the strand in the migration domain.
Wei Xiao +4 more
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