Results 21 to 30 of about 44,186 (249)
Timed Pulses in DNA Strand Displacement Reactions. [PDF]
J Am Chem Soc, 2023 Inspired by naturally occurring regulatory mechanisms that allow complex temporal pulse features with programmable delays, we demonstrate here a strategy to achieve temporally programmed pulse output signals in DNA-based strand displacement reactions (SDRs).
Bucci J +4 more
europepmc +4 more sources
Logical Reasoning Based on DNA Strand Displacement [PDF]
Jisuanji kexue, 2022 A computational model for logical reasoning is proposed based on DNA strand displacement reactions.Firstly,this way does not rely on fluorescent labeling or other DNA experimental technique.The corresponding relationship between the concentration change ...
WU Li-bo, HUANG Yu-fang
doaj +1 more source
Dissipative Control over the Toehold‐Mediated DNA Strand Displacement Reaction [PDF]
Angewandte Chemie - International Edition, 2022 Erica Del Grosso +2 more
exaly +2 more sources
Directing Uphill Strand Displacement with an Engineered Superhelicase. [PDF]
ACS Synth Biol, 2023 The ability to finely tune reaction rates and binding energies between components has made DNA strand displacement circuits promising candidates to replicate the complex regulatory functions of biological reaction networks. However, these circuits often lack crucial properties, such as signal turnover and the ability to transiently respond to ...
Hall-Thomsen H +5 more
europepmc +3 more sources
Strand Displacement Activity of PrimPol [PDF]
International Journal of Molecular Sciences, 2020 Human PrimPol is a unique enzyme possessing DNA/RNA primase and DNA polymerase activities. In this work, we demonstrated that PrimPol efficiently fills a 5-nt gap and possesses the conditional strand displacement activity stimulated by Mn2+ ions and accessory replicative proteins RPA and PolDIP2. The DNA displacement activity of PrimPol was found to be
Elizaveta O. Boldinova +6 more
openaire +2 more sources
Biomolecules, 2022 DNA and RNA strand exchange is a process of fundamental importance in biology. Herein, we used a FRET-based assay to investigate, for the first time, the stand exchange kinetics of natural DNA, natural RNA, and locked nucleic acid (LNA)-modified DNA ...
Ivana Domljanovic +4 more
doaj +1 more source
Sequencing double-stranded DNA by strand displacement [PDF]
Nucleic Acids Research, 1997 Duplex probes with five base single-stranded overhangs can capture dsDNA targets from type IIS restriction nuclease digests. Ligation generates a predesigned nick site, where DNA polymerase can generate sequencing ladders by strand displacement or nick translation in the presence of trace amounts of dideoxynucleotides.
D J, Fu +3 more
openaire +2 more sources
Sequential super-resolution imaging using DNA strand displacement. [PDF]
PLoS ONE, 2018 Sequential labeling and imaging in fluorescence microscopy allows the imaging of multiple structures in the same cell using a single fluorophore species.
Sandeep Pallikkuth +6 more
doaj +1 more source
Modelling Toehold-Mediated RNA Strand Displacement [PDF]
Biophysical Journal, 2015 We study the thermodynamics and kinetics of an RNA toehold-mediated strand displacement reaction with a recently developed coarse-grained model of RNA. Strand displacement, during which a single strand displaces a different strand previously bound to a complementary substrate strand, is an essential mechanism in active nucleic acid nanotechnology and ...
Šulc, Petr +4 more
openaire +5 more sources
DNA Logic Multiplexing Using Toehold-Mediated Strand Displacement
IEEE Access, 2020 Since the discovery of the DNA Strand Displacement mechanism, researchers have implemented a lot of applications, such as DNA computing, DNA Circuits, Logic gates, and Chemical Reaction network.
Congzhou Chen +4 more
doaj +1 more source