Results 21 to 30 of about 812,407 (248)

Principles and Applications of Nucleic Acid Strand Displacement Reactions

Chemical Reviews, 2019
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the study and application of nucleic acid strand-displacement reactions.
Friedrich Simmel, Bernard Yurke
exaly   +2 more sources

DNA dynamics and computation based on toehold-free strand displacement

Nature Communications, 2021
Synthetic DNA constructs can to used to recognise and respond to input signals. Here the authors present complex DNA nanostructures with toehold-free strand displacement for generation of ON/OFF switches and Boolean gates.
Hong Kang, Tong Lin, Xiaojin Xu, Qing-Shan Jia, Richard Lakerveld, Bryan Wei   +5 more
doaj   +2 more sources

Structural basis for intrinsic strand displacement activity of mitochondrial DNA polymerase [PDF]

Nature Communications
Members of the Pol A family of DNA polymerases, found across all domains of life, utilize various strategies for DNA strand separation during replication.
Ashok R. Nayak, Viktoriia Sokolova, Sirelin Sillamaa, Karl Herbine, Juhan Sedman, Dmitry Temiakov   +5 more
doaj   +2 more sources

Sequential super-resolution imaging using DNA strand displacement. [PDF]

PLoS ONE, 2018
Sequential labeling and imaging in fluorescence microscopy allows the imaging of multiple structures in the same cell using a single fluorophore species.
Sandeep Pallikkuth, Cheyenne Martin, Farzin Farzam, Jeremy S Edwards, Matthew R Lakin, Diane S Lidke, Keith A Lidke   +6 more
doaj   +2 more sources

Kinetics of RNA and RNA:DNA Hybrid Strand Displacement [PDF]

ACS Synthetic Biology, 2021
In nucleic acid nanotechnology, strand displacement is a widely used mechanism where one strand from a hybridized duplex is exchanged with an invading strand that binds to a toehold, a single-stranded region on the duplex.
Hao Yan, Thomas E. Ouldridge, Junyi Che
exaly   +2 more sources

DNA strand displacement based computational systems and their applications [PDF]

Frontiers in Genetics, 2023
DNA computing has become the focus of computing research due to its excellent parallel processing capability, data storage capacity, and low energy consumption characteristics.
Congzhou Chen, Jinda Wen, Zhibin Wen, Sijie Song, Xiaolong Shi   +4 more
doaj   +2 more sources

Logical Reasoning Based on DNA Strand Displacement [PDF]

Jisuanji kexue, 2022
A computational model for logical reasoning is proposed based on DNA strand displacement reactions.Firstly,this way does not rely on fluorescent labeling or other DNA experimental technique.The corresponding relationship between the concentration change ...
WU Li-bo, HUANG Yu-fang
doaj   +1 more source

Digital DNA Strand Displacement for Molecular Computing [PDF]

, 2023
Multiplexed analysis of feature biomarkers enhances the accuracy of molecular diagnostic results. Molecular computing systems exhibited potentials for intelligent analysis of multiplexed biomarkers.
Xin, Su, Jiayu, Yang, Yumin, Yan, Hongyang, Zhao, Xinmiao, Kang, Jiong, Huang, Huixiao, Yang, Linghao, Zhang   +7 more
core   +2 more sources

Natural and Modified Oligonucleotide Sequences Show Distinct Strand Displacement Kinetics and These Are Affected Further by Molecular Crowders

Biomolecules, 2022
DNA and RNA strand exchange is a process of fundamental importance in biology. Herein, we used a FRET-based assay to investigate, for the first time, the stand exchange kinetics of natural DNA, natural RNA, and locked nucleic acid (LNA)-modified DNA ...
Ivana Domljanovic, Alessandro Ianiro, Curzio Rüegg, Michael Mayer, Maria Taskova   +4 more
doaj   +1 more source

Double Synchronization Based on DNA Strand Displacement Reaction

IEEE Access, 2020
As an important part of biological computing, DNA strand displacement technology is used to construct complex biochemical circuits. Reversible molecular chemical reactions are basic chemical reactions.
Junwei Sun, Zhenzhen Zhang, Aolong Lv, Yanfeng Wang   +3 more
doaj   +1 more source