Results 311 to 320 of about 6,016,549 (343)
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Cardiomyocyte DNA synthesis and binucleation during murine development.
American Journal of Physiology, 1996Cardiomyocyte DNA synthesis and binucleation indexes were determined during murine development. Cardiomyocyte DNA synthesis occurred in two temporally distinct phases.
M. Soonpaa+4 more
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Chemical synthesis of DNA [PDF]
Overview of DNA synthesis methodologies and polymer-supported synthesis of DNA using deoxynucleoside phosphoramidites.
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The fidelity mechanism of DNA synthesis
Hereditas (Beijing), 2012Accurate DNA synthesis is vital to maintain genome stability and ensure propagation of species. Synthetic errors have far reaching consequences. Therefore, DNA synthesis is remarkably accurate. The high fidelity is mainly achieved through three steps: ① nucleotide selection, which is based on hydrogen, base pair shape, or some other elements; ② 3'→5 ...
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2013
In DNA templated synthesis (DTS) the effective local concentration of two or more reactants tethered to oligonucleotide strands is regulated by direct hybridization of the strands or by hybridization to a common template, bringing the reactants in close proximity.
Thomas Tørring+2 more
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In DNA templated synthesis (DTS) the effective local concentration of two or more reactants tethered to oligonucleotide strands is regulated by direct hybridization of the strands or by hybridization to a common template, bringing the reactants in close proximity.
Thomas Tørring+2 more
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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
Nature, 1991S. Shibutani, M. Takeshita, A. Grollman
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2018
Human DNA polymerase η (pol η) is the gene product that is altered in the variant form of xeroderma pigmentosum. Pol η has a structure that can accommodate the cyclobutane pyrimidine dimer, the most prominent ultraviolet-induced DNA lesion. Pol η catalyzes efficient and accurate translesion DNA synthesis (TLS) under the fine control of systems ...
Fumio Hanaoka, Chikahide Masutani
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Human DNA polymerase η (pol η) is the gene product that is altered in the variant form of xeroderma pigmentosum. Pol η has a structure that can accommodate the cyclobutane pyrimidine dimer, the most prominent ultraviolet-induced DNA lesion. Pol η catalyzes efficient and accurate translesion DNA synthesis (TLS) under the fine control of systems ...
Fumio Hanaoka, Chikahide Masutani
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DNA synthesis in nuclear protrusions
Experimental Cell Research, 1971Abstract The broken ends of mitotic bridges persisting into interphase often form nuclear protrusions in HeLa cells: DNA synthesis localised at the protrusions may take place in S or in G2 as late as prophase or thereabouts. These nuclear sites are found to be associated with a ring chromosome in a number of cases.
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The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
Nature, 2001J. Falck+4 more
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