Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway
Animal Models and Experimental Medicine, EarlyView.This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.The luminescence of a heterometallic d‐s {Cu2I2Na2} phosphane‐phosphinate aggregate is regulated by an interplay of Na+–π/I– contacts and reversible coordination of oxygen‐containing organic molecules to Na ions. Structural variations caused by the incoming guest lead to a wide and selective variation of the emission color and illustrate a new approach
Henna Korhonen +10 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui +9 more
wiley +2 more sources
Correction to 'TORCphysics: a physical model of DNA-topology-controlled gene expression'. [PDF]
Nucleic Acids Reseuropepmc +1 more source
Tethered Particle Motion: An Easy Technique for Probing DNA Topology and Interactions with Transcription Factors. [PDF]
Methods Mol Biol, 2018 Kovari DT, Yan Y, Finzi L, Dunlap D.
europepmc +1 more source
Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology. [PDF]
Mol Oncol, 2019 Ahmed SM, Dröge P.
europepmc +1 more source
The interplay between DNA topology and accessory factors in site-specific recombination in bacteria and their bacteriophages. [PDF]
Sci Prog, 2016 Dorman CJ, Bogue MM.
europepmc +1 more source
The Impact of DNA Topology and Guide Length on Target Selection by a Cytosine-Specific Cas9. [PDF]
ACS Synth Biol, 2017 Tsui TKM, Hand TH, Duboy EC, Li H.
europepmc +1 more source
Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation
Angewandte Chemie International Edition, EarlyView.A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi +6 more
wiley +1 more source
Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes
Journal of Applied Polymer Science, EarlyView.Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis +1 more
wiley +1 more source