Results 181 to 190 of about 121,527 (239)
Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation
Angewandte Chemie International Edition, EarlyView.A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi +6 more
wiley +1 more source
Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes
Journal of Applied Polymer Science, EarlyView.Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis +1 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Arhinolemur scalabrinii† Ameghino, 1898 was originally described as a strepsirrhine primate (Mammalia) but has been recognized as an anostomid fish since 2012. It remains the only extinct anostomid species known from complete cranial material.
Karen M. Panzeri +8 more
wiley +1 more source
Animal Research and One Health, EarlyView.This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun +6 more
wiley +1 more source
Animal Research and One Health, EarlyView.This study analyzed the spleen transcriptomes of different chicken breeds, identified key differentially expressed genes (EGR1, FOS, and DUSP1) that regulate resistance to Salmonella infection, and elucidated the underlying regulatory mechanisms, thereby providing new targets for disease‐resistant breeding in poultry.
Zixuan Wang +8 more
wiley +1 more source
Animal Research and One Health, EarlyView.Seven‐year surveillance reveals a cold‐adapted OsHV‐1 lineage in blood clams, with disease onset at 13°C—3–5°C lower than in oysters—and identifies asymptomatic carriers and facility effluent as key transmission routes. ABSTRACT Ostreid herpesvirus 1 (OsHV‐1) poses a major threat to bivalve aquaculture, but its impact on blood clams (Anadara ...
Xiang Zhang +7 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
How loop lengths shape topological preferences of two-tetrad G-quadruplexes. [PDF]
Nucleic Acids ResWoś A +6 more
europepmc +1 more source
Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling
Biotechnology and Bioengineering, EarlyView.ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana +4 more
wiley +1 more source
Topological rules and anomalies in intramolecular G-quadruplex folding: a comprehensive study. [PDF]
Nucleic Acids ResGranzhan A, Mouawad L.
europepmc +1 more source