Results 191 to 200 of about 119,671 (240)

A WGCNA‐Based Approach to Identify Hub Genes Associated With TNM Staging in Urothelial Bladder Carcinoma

Cancer Nexus, EarlyView.
ABSTRACT In this study, we identified gene modules and representative candidate biomarkers linked to clinical progression in patients with UBC. Weighted gene co‐expression network analysis (WGCNA) was used to identify gene modules associated with TNM staging in UBC patients.
Arshia Azmoudeh
wiley   +1 more source

Spectroscopic Investigation of the Interaction Between a Spermine-Functionalized Porphyrin and TERRA G-Quadruplexes. [PDF]

Int J Mol Sci
Travagliante G, Gaeta M, Campanella G, Yatsunyk LA, D'Urso A.   +4 more
europepmc   +1 more source

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei

Developmental Dynamics, EarlyView.
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Jeong Han Lee, Ebenezer N. Yamoah, Jennifer Kersigo, Karen Elliott, Niya LaRoda, Gabriela Pavlinkova, Bernd Fritzsch   +6 more
wiley   +1 more source

Actively Induced Supercoiling Can Slow Down Plasmid Solutions by Trapping the Threading Entanglements. [PDF]

ACS Nano
Staňo R, Rusková R, Račko D, Smrek J.
europepmc   +1 more source

Metal‐Free Ligand‐Centered Radical Scavenging in Pyridine‐Modified Tetraaza Macrocycles

European Journal of Organic Chemistry, EarlyView.
Ligand‐centered hydrogen‐atom transfer in pyridinophane macrocycles generates delocalized radicals, with Py2N2 enabling cooperative captodative stabilization and enhanced DPPH• quenching. Pyridine‐modified tetraaza macrocycles are widely studied as ligand platforms for metal coordination, yet their intrinsic redox and radical reactivity in the absence ...
Christina Mantsorov, Hannah K. Pyle, Tahmina Afroz, Caden‐Jack N. Walls, Nora Del Bosque, Timothy M. Schwartz, Chelsea N. Miller, Kristof Pota, Benjamin G. Janesko, Kayla N. Green   +9 more
wiley   +1 more source

TopCas: Topology-Gated Cas12a via DNA-RNA Chimeric Circular crRNA for Amplification-Free Nucleic Acid Detection and Conditional Gene Editing. [PDF]

Adv Sci (Weinh)
Zhang S, Sun W, Xiao T, Wang Y, Wu X, Chen H, Chen M, Zhang J.   +7 more
europepmc   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Microbial Primer: Bacterial DNA supercoiling. [PDF]

Microbiology (Reading)
Dorman CJ.
europepmc   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Assessing the Potential of Ancient Protein Sequences in the Study of Hominid Evolution. [PDF]

Genome Biol Evol
Patramanis I, Skov L, Cappellini E, Racimo F.   +3 more
europepmc   +1 more source