Results 161 to 170 of about 617,524 (203)
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Mechanisms of DNA virus infection entry and early events
Frontiers in Bioscience, 2002The cellular components engaged in entry of viruses has been an area of intense investigation in recent years. We examine the entry and receptors used for well-studied and prevalent human DNA viruses adenoviruses, poxviruses and two herpesviruses- herpes simplex virus and Epstein-Barr virus. Little is yet known about the entry or early events for other
A Oveta, Fuller, Pilar, Perez-Romero
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The infectivity of nuclear polyhedrosis virus DNA
Annales de l'Institut Pasteur / Virologie, 1981Summary Trichoplusia ni multiply-enveloped nuclear polyhedrosis virus DNA is infectious provided it is circular and double-stranded. This has been shown by comparing linear, nicked circular (nc) and covalently closed (cc) DNA, with single-stranded derivatives, and by comparing naturally cccurring forms with forms generated enzymatically with ligase
D.C. Kelly, X. Wang
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Virus-specific RNA and DNA in nuclei of cells infected with fowlpox virus
Virology, 1976Abstract Poxviruses appear to be assembled exclusively in the cytoplasm of infected cells, and it has been generally held that all replicative events are restricted to the cytoplasm. Previous work in this laboratory has shown that fowlpox virus (FPV) stimulates DNA synthesis both in vivo and in vitro , which, together with the ability of FPV to ...
L G, Gafford, C C, Randall
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Presence of hepatitis C Virus DNA sequences in the DNA of infected patients
European Journal of Clinical Investigation, 2008ABSTRACTBackground Hepatitis C virus (HCV) consists of a single positive RNA molecule. In the present study we investigated the possibility that HCV may undergo integration into the genomic DNA of infected cells.Materials and methods HCV(+) patients (n = 51) and 21 HCV(–) controls were investigated for HCV integration.
R, Zemer +3 more
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DNA-PK senses DNA virus infection in human cells
The Journal of Immunology, 2021Abstract The type I interferon (IFN-I) response to virus infection is initiated by the detection of nucleic acids by intracellular pattern recognition receptors (PRRs). The sensing of DNA viruses by PRRs is carried out by a number of DNA-binding PRRs that signal via the adaptor protein stimulator of interferon genes (STING) to drive IFN ...
Brian J Ferguson +3 more
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Chemotherapy of DNA virus infections
1999Abstract In recent years there have been considerable advances in the development of effective antiviral drugs. Much of this progress has been driven by the need to combat human immunodeficiency virus (HIV) infection, but there are currently nearly thirty antiviral agents in clinical development or licensed for use in humans against ...
Patricia A Cane, Deenan Pillay
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Synthesis of DNA and Protein in Cells infected with Vaccinia Virus
Nature, 1966THE study of DNA and protein synthesis in cells infected with vaccinia virus has previously led to contradictory results. Both increase1,2 and decrease3–5 of DNA and protein synthesis have been demonstrated. This may be due to the use of different cell strains and stages of virus infection.
V M, Zhdanov +3 more
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Virus DNA and host DNA in polyoma virus-infected cells at high temperature
Virology, 1972Abstract Incubation of mouse kidney (MK) cells at 41.6 ± 0.1° led to a rapid inhibition of DNA synthesis. Infection with the SP 2 mutant of polyoma virus (PV) at 41.6° induced the cells to synthesize DNA again. However, production of infectious SP 2 DNA or infectious virions was reduced under these conditions.
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Control of DNA synthesis in cells infected with polyoma virus
Virology, 1968Abstract It had previously been established that cell DNA synthesis is inhibited in growing mouse embryo cells productively infected at high multiplicity with polyoma TSP1. In the present study it was found that cell DNA was stimulated in the same cell-virus system, but infected at low multiplicity ( Branton and Sheinin, 1968 ).
P E, Branton, R, Sheinin
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DNA vaccination against respiratory influenza virus infection
Vaccine, 2001DNA vaccination using plasmid encoding the hemagglutinin (HA) gene of influenza A/PR/8/34 virus to induce long-lasting protective immunity against respiratory infection was evaluated in this study. Using liposomes as carriers, the efficacy of DNA vaccines was determined using a lethal influenza infection model in mice.
J P, Wong +7 more
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