Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response
Biochemistry Research International, 2011 Membrane rafts are small (10–200 nm) sterol- and sphingolipid-enriched domains that compartmentalize cellular processes. Membrane rafts play an important role in viral infection cycles and viral virulence.
Tadanobu Takahashi, Takashi Suzuki
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Cytokine production and signaling pathways in respiratory virus infection
Frontiers in Microbiology, 2013 It has been confirmed that respiratory virus infections can induce abberant cytokine production in the host. These cytokines may be associated with both elimination of the virus and complications in the host, such as virus-induced asthma.
Hirokazu eKimura +4 more
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Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques. [PDF]
, 2019 Herpes simplex virus 2 (HSV-2) is a common sexually transmitted infection with a highly variable clinical course. Many infections quickly become subclinical, with episodes of spontaneous virus reactivation.
Burgener, Adam +15 more
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IL28B is associated with outcomes of chronic HBV infection [PDF]
, 2015 Purpose The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes.
Chi, Xiumei +11 more
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DNA in Uninfected and Virus-Infected Cells Complementary to Avian Tumor Virus RNA [PDF]
Proceedings of the National Academy of Sciences, 1971 The 70S RNA component of several avian tumor viruses was hybridized with DNA extracted from avian tumor virus-infected and uninfected chicken and Japanese quail cells. Tritium-labeled 70S RNAs from Rous sarcoma virus (RSV), Rous associated virus-1 (RAV-1), RAV-60, and Schmidt-Ruppin-RSV (SR-RSV) hybridize from 3 to 10 times more with DNA ...
P N, Rosenthal +4 more
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Human and bovine respiratory syncytial virus vaccine research and development [PDF]
, 2008 Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine +2 more
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Infectivity, Oncogenicity and Transforming Ability of BK Virus and BK Virus DNA
Journal of General Virology, 1976 The human papovavirus, BK, appeared weakly oncogenic in newborn hamsters and was able to induce in vitro transformation of rat kidney cells. The infectivity of BK virus DNA was determined by employing the DEAE-dextran method. In human embryonic cells the infectivity was approx. 10(5) p.f.u./mug of DNA.
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Functions of DNA damage machinery in the innate immune response to DNA virus infection [PDF]
Current Opinion in Virology, 2015 DNA is potently immunostimulatory, and self-DNA is packaged in the nucleus or mitochondria allowing it to remain silent to cell-intrinsic sensors. However, damaged or mislocalised self-DNA is sensed by our innate immune systems, resulting in the production of type I interferons (IFNI), chemokines and inflammatory cytokines.
Trigg, Ben J, Ferguson, Brian J
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The Multifarious Role of 14-3-3 Family of Proteins in Viral Replication
Viruses, 2020 The 14-3-3 proteins are a family of ubiquitous and exclusively eukaryotic proteins with an astoundingly significant number of binding partners. Their binding alters the activity, stability, localization, and phosphorylation state of a target protein. The
Kavitha Ganesan Nathan, Sunil K. Lal
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Viral microRNA effects on persistent infection of human lymphoid cells by polyomavirus SV40. [PDF]
PLoS ONE, 2018 Polyomaviruses, including simian virus 40 (SV40), display evidence of lymphotropic properties. This study analyzed the nature of SV40-human lymphocyte interactions in established cell lines and in primary lymphocytes.
Adrienne L McNees +5 more
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