Immune Response to Herpes Simplex Virus Infection and Vaccine Development
Herpes simplex virus (HSV) infections are among the most common viral infections and usually last for a lifetime. The virus can potentially be controlled with vaccines since humans are the only known host.
Anthony C. Ike +4 more
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Successful Treatment of Severe Adenoviral ARDS Using Cidofovir in a Case with Cerebral Palsy
Adenovirus is a non-enveloped, double-stranded DNA virus that can cause infections in the upper and lower respiratory tract, conjunctiva, and gastrointestinal tract. Adenovirus infections are usually mild but may cause mortality and morbidity, especially
Emrah Gün +7 more
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Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. [PDF]
On September 22, 2008, a physician on Prince of Wales Island, Alaska, notified the Alaska Department of Health and Social Services (ADHSS) of an unusually high number of adult patients with recently diagnosed pneumonia (n = 10), including three persons ...
Barnard, Dale L +8 more
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Different behaviour of BK-virus infection in liver transplant recipients [PDF]
Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts ...
MITTERHOFER, Anna Paola +3 more
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A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. [PDF]
Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species induce IFN via separate pathways, the mechanisms by which these pathways are differentially ...
Aliyari, Saba Roghiyh +9 more
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hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA
The heterogeneous nuclear ribonucleoprotein (hnRNPA2B1, hereafter A2B1) was identified as a novel nuclear DNA sensor that mediates antiviral immunity by recognizing viral DNA in the nucleus. However, it remains largely unclear whether A2B1 could function
Xin-bo Huang +6 more
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Mycoviruses as Triggers and Targets of RNA Silencing in White Mold Fungus Sclerotinia sclerotiorum
This study aimed to demonstrate the existence of antiviral RNA silencing mechanisms in Sclerotinia sclerotiorum by infecting wild-type and RNA-silencing-deficient strains of the fungus with an RNA virus and a DNA virus.
Pauline Mochama +3 more
doaj +1 more source
The SEN virus (SENV) has been linked to transfusion-associated non-A-E hepatitis; however, information regarding SENV infections in patients with thalassemia, particularly in those with hepatitis virus co-infections, remains limited.
Mushtak T S Al-Ouqaili +2 more
doaj +1 more source
Role of glutathionylation in infection and inflammation [PDF]
Glutathionylation, that is, the formation of mixed disulfides between protein cysteines and glutathione (GSH) cysteines, is a reversible post-translational modification catalyzed by dierent cellular oxidoreductases, by which the redox state of the cell
Baldelli, S. +5 more
core +1 more source
Multicenter clinical evaluation of the Luminex Aries Flu A/B & RSV assay for pediatric and adult respiratory tract specimens [PDF]
Influenza A and B viruses and respiratory syncytial virus (RSV) are three common viruses implicated in seasonal respiratory tract infections and are a major cause of morbidity and mortality in adults and children worldwide. In recent years, an increasing
Buller, Richard S +6 more
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