Results 131 to 140 of about 57,052 (243)

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie   +12 more
wiley   +1 more source

A unifying framework for intelligent DNS management

open access: yes, 2009
[[abstract]]The Domain Name System (DNS) is a special kind of distributed directory service for people to create and access the network information systems by (1) allowing local control of its segments and (2) making each segment?s data available on the ...
C. S. Chen; S. S. Tseng; J. L. Liu
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Design and implementation of an intelligent DNS management system [PDF]

open access: yes, 2009
[[abstract]]In this paper, we focus on the design and building of iDNS-MS by using knowledge-based system and ontological engineering technologies. iDNS-MS, developed by using web interface and expert system technology, is a unifying environment for ...
C. L. Liu; S. S. Tseng; C. S. Chen
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Metal Battery Anode: Rich in Electrons, Rich in Problems: A Critical Review from Industrial Perspectives

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
Metal‐anode batteries using Li, Na, Mg, and Ca offer exceptionally high energy density, but dendrites, unstable interphases, cracking, and pore formation hinder durability and safety. This review shows how careful electrolyte and interphase design can stabilize these reactive metals.
Jian Pan   +3 more
wiley   +1 more source

Microorganism‐based bioinput enhances wheat yield and drought resilience

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 3, September 2026.
Abstract Agricultural bioinputs can enhance plant nutrition, productivity, and tolerance to water deficit, providing a sustainable alternative to conventional crop management. This study evaluated the technical feasibility of the microorganism‐based bioinput Bio‐X Agricultura Única for improving wheat (Triticum aestivum L.) productivity and resistance ...
Moises Alves de Souza   +1 more
wiley   +1 more source

The Cog‐Aging: a 15‐year cohort study of cognition in Brazilian older adults

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract BACKGROUND Prevalence of dementia is higher in low‐ and middle‐income countries (LMICs). However, longitudinal studies characterizing cognitive decline and its clinical and epidemiological predictors remain scarce in Brazil. METHODS Participants were enrolled from 2011 to 2025 and followed through May 2026.
Gabriela Tomé Oliveira Engelmann   +27 more
wiley   +1 more source

A DNS study of radiation effects on the turbulent premixed flame properties

open access: yes, 2015
Two-dimensional (2D) direct numerical simulation (DNS) is adopted to study the radiation effects on a freely propagating turbulent premixed syngas flame.
Im, Hong G.   +4 more
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Arthroscopic All‐Inside/All‐Suture Repair of Complete Radial Tear of the Lateral Meniscus Using a Percutaneous Single‐Needle Technique

open access: yesArthroscopy Techniques, Volume 15, Issue 9, September 2026.
Abstract Radial tears of the lateral meniscus have limited healing potential and unfavorable biomechanics, and current suture constructs that use capsular rip‐stop stitches may increase meniscal extrusion and constrain native motion. This technical note describes an all‐inside, crossed, meniscus‐based repair for complete or near‐complete radial tears ...
Diego Sánchez Cruz   +3 more
wiley   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

open access: yesBiotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen   +2 more
wiley   +1 more source

A DNS ligáz IV enzim deléciója által okozott fenotípusos változások megjelenése eukarióta modellszervezetekben

open access: yes, 2018
A munkám célja az volt, hogy a humán DNS ligáz IV gén és a hasadó élesztő Schizosaccharomyces pombe, valamint a sarjadzó élesztő Saccharomyces cerevisiae-ben megtalálható ortológjait bemutassam, szemléltessem a gén deléciója és a fehérje károsodása ...
Balogh, Ágnes Róza
core  

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