Results 121 to 130 of about 15,919 (234)

Is the use of warfarin becoming obsolete?

Journal of Community Hospital Internal Medicine Perspectives, 2021
Tarek Haykal, Smit S. Deliwala, Thomas L. Ortel   +2 more
doaj   +1 more source

Evaluating DOAC dipstick testing in the management of acute stroke: protocol for a multicentre, prospective, observational registry study

BMJ Open
Introduction Direct oral anticoagulants (DOACs) are preferred over vitamin K antagonists for stroke prophylaxis in non-valvular atrial fibrillation. Yet, DOAC use is regarded as a contraindication for intravenous thrombolysis in acute ischaemic stroke ...
Philip Choi, Helen Dewey, Edward Patrick Callaly, Peter Shuangyue Tan, Emily Schembri, Marija Borosak   +5 more
doaj   +1 more source

Assessing the efficacy of a single-cycle measurement and adjustment strategy for direct oral anticoagulants in frail older patients: rationale and design of the DOAC-FRAIL randomized controlled trial

Research and Practice in Thrombosis and Haemostasis
Background: Frail older patients are at high risk of both thromboembolism and bleeding, making anticoagulant therapy challenging. Direct oral anticoagulants (DOACs) have largely replaced vitamin K antagonists because of comparable efficacy and lower ...
Fabienne J.H. Magdelijns, Melanie J. de Jong, Kristien Winckers, Astrid D.H. Brys, Dionne C.W. Braeken, Sander M.J. van Kuijk, Henri M.H. Spronk, Hans Bosman, Daisy J.A. Janssen, Robin M.J.M. van Geel, Dave Hellenbrand, Hugo ten Cate, Yvonne Henskens   +12 more
doaj   +1 more source

Exploring therapeutic drug monitoring-guided direct oral anticoagulant use in patients with non-small cell lung cancer treated with small-molecule inhibitors

Thrombosis Update
Background: Patients with advanced non-small cell lung cancer are at increased risk of venous thromboembolism (VTE) and often receive direct oral anticoagulants (DOACs) for thromboprophylaxis.
Paul D. Kruithof, Anouk EWK. Dontje, Maud MA. Salmans, Kristien Winckers, Wouter H. van Geffen, Lizza EL. Hendriks, Sander Croes, Rob ter Heine, Robin van Geel   +8 more
doaj   +1 more source

Analysis of patient adherence to treatment by DOAC II

, 2023
6 Abstract Analysis of patient adherence to treatment by DOAC II Author: Natália Janáčková Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Simona Dvořáčková, Ph.D., Mgr.
Janáčková, Natália
core  

Direct oral anticoagulants (DOAC) for prevention of recurrent arterial or venous thromboembolic events (ATE/VTE) in myeloproliferative neoplasms

, 2020
In patients with \(\it BCR-ABL\)-negative myeloproliferative neoplasms (MPN), arterial or venous thromboembolic events (ATE/VTE) are a major burden. In order to control these complications, vitamin K antagonists (VKA) are widely used.
Engelhardt, Carina, Griesshammer, Martin (Prof. Dr. med.), Sadjadian, Parvis (Dr. med.), Wille, Kai (Dr. med.), Deventer, Eva (Dr. med.), Kolatzki, Vera, Hünerbein, Karlo R. (Dr. med.), Becker, Tatjana   +7 more
core   +1 more source

Some characteristics of NVAF patients enrolled in START-Register, compared to those in the GARFIELD Registry and in randomized trials on DOAC.

, 2015
DOAC = direct oral anticoagulantCrCl = creatinine clearanceData are expressed as mean ± SD, or median (IQR), or %; NA = not available* = patients with ...
Gualtiero Palareti (743533), Vittorio Pengo (444660), Alberto Tosetto (743530), Armando Tripodi (743531), Emilia Antonucci (743529), Daniela Poli (331106), Francesco Marongiu (743532), Nicola Magrini (646515)   +7 more
core   +1 more source

Disparities in the real-world prescription pattern of oral anticoagulants for US Medicare beneficiaries: a geospatial analysis

BMJ Open
Objectives This study was conducted to examine urban–rural differences in the real-world prescribing pattern of oral anticoagulants and geographic variations in the prescribing pattern among clinicians serving Medicare beneficiaries in the USA.Design A ...
Yong Zhu, Dong Liang, Jingrui Zou
doaj   +1 more source

Perioperative management of patients taking direct oral anticoagulants: challenges in high-bleed-risk surgery and neuraxial anesthesia

Bleeding, Thrombosis and Vascular Biology
Perioperative direct oral anticoagulants (DOACs) management has been supported by guidelines, however there is still limited high quality data to inform best practices regarding the perioperative management of DOAC-treated patients who need a high-bleed-
Maria P. Ntalouka, Eleni M. Arnaoutoglou, James D. Douketis   +2 more
doaj   +1 more source

Effects of DOACs on Mouse Melanoma Metastasis and the Inhibitory Mechanism of Edoxaban, a Factor Xa-Specific DOAC

TH Open
AbstractDirect oral anticoagulants (DOACs) have been widely used in patients with thromboembolism. We previously reported that among DOACs, edoxaban (EDX), a factor Xa (FXa)-specific DOAC, most effectively inhibited the growth of syngeneic non-metastatic murine colon cancer cells implanted in mice via the protease-activated receptor 2 (PAR2) pathway ...
Hiramoto, Keiichi, Watanabe, Taisei, Imai, Masashi, Suzuki, Koji   +3 more
openaire   +2 more sources