Results 181 to 190 of about 21,302 (228)
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Interactions Between Direct Oral Anticoagulants (DOACs) and Antiseizure Medications: Potential Implications on DOAC Treatment

CNS Drugs, 2023
The use of direct oral anticoagulants (DOACs) is increasing because of their superior efficacy and safety compared with vitamin K antagonists. Pharmacokinetic drug interactions, particularly those involving cytochrome P450- mediated metabolism and P-glycoprotein transport, significantly affect the efficacy and safety of DOACs.
Rachel Goldstein   +5 more
openaire   +3 more sources

DOAC compared with warfarin for VTE in patients with obesity: a retrospective cohort study conducted through the VENUS network

Journal of Thrombosis and Thrombolysis, 2023
The effectiveness and safety of direct oral anticoagulants (DOAC) compared with warfarin remains uncertain in obese patients. We assessed the comparative effectiveness and safety of DOACs with warfarin for the treatment of VTE among obese patients.
K. Martin   +8 more
semanticscholar   +1 more source

Resolving DOAC interference on antithrombin activity testing on a FXa based method by the use of activated carbon.

Clinica chimica acta; international journal of clinical chemistry, 2022
BACKGROUND Direct oral anticoagulants (DOACs) may cause falsely increased levels of antithrombin (AT) activity depending on the AT activity method and the specific target of the DOAC.
Jill Vercruyssen, P. Meeus, E. Bailleul
semanticscholar   +1 more source

Impact of a commercially available DOAC absorbent on two integrated procedures for lupus anticoagulant detection.

Thrombosis Research, 2021
BACKGROUND Lupus anticoagulant (LA)-detection in anticoagulated patients is an unmet need, which becomes even more cogent with the introduction of direct oral anticoagulants (DOAC) that may lead to false-positive results.
A. Tripodi   +8 more
semanticscholar   +1 more source

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