Results 101 to 110 of about 5,988 (201)

Effect of Direct Oral Anticoagulants in Patients with Splanchnic Vein Thrombosis: A Systematic Reviews and Meta-Analysis

Clinical and Applied Thrombosis/Hemostasis
Background Since several studies have examined the use of direct oral anticoagulants (DOACs) in treating patients with splanchnic vein thrombosis (SVT), we conducted a meta-analyses to assess the safety and efficacy of DOACs compared to vitamin K ...
Yun Wan MS, Linjuan Guo MD, Meimei Xiong MS   +2 more
doaj   +1 more source

Feasibility and Safety Profile of Non‐anesthesiologist‐administered Propofol During Colorectal Endoscopic Submucosal Dissection: A Single‐center Study of 454 Procedures

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Studies of non‐anesthesiologist‐administered propofol (NAAP) during colorectal endoscopic submucosal dissection (ESD) are scarce, particularly in the elderly. We evaluated its feasibility across a broad age range and identified factors associated with sedation‐related adverse events.
Yumi Kishi, Mayo Tanabe, Naoyuki Uragami, Daijiro Shiomi, Mai Fukuda, Miho Kurahashi, Toshiki Hanzawa, Michimasa Yamaguchi, Mikio Muraoka, Hatsuka Nakamura, Rei Miyake, Yukiko Okada, Yoichi Toyoda, Akiko Toshimori, Takayoshi Ito, Noboru Yokoyama, Haruhiro Inoue   +16 more
wiley   +1 more source

Perioperative management of DOACs in vascular surgery: A practical approach

, 2018
Background: Approximately 10–15% of patients on DOACs have to interrupt their anticoagulant before an invasive procedure every year. The perioperative management and monitoring of DOACs have proved to be challenging, as differences in patients’ status ...
Kouvelos G., Matsagkas M., Rousas N., Nana P., Mpatzalexis K., Stamoulis K., Giannoukas A., Arnaoutoglou E.
core   +1 more source

Medication Adherence to Direct Oral Anticoagulants: Extent and Impact of Side Effects

Patient Preference and Adherence
Bas JW van de Steeg,1 Anne C Esselink,2 Hugo AJM de Wit,1 Cornelis Kramers,1 Bart JF van den Bemt3 1Department of Clinical Pharmacy, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands; 2Department of Internal Medicine, Canisius Wilhelmina Hospital ...
van de Steeg BJW, Esselink AC, de Wit HAJM, Kramers C, van den Bemt BJF   +4 more
doaj  

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3733-3758, November 2026.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies, Elin Haf Davies, Dyfrig A. Hughes   +2 more
wiley   +1 more source

Efficacy and Safety of Apixaban Thromboprophylaxis According to Baseline Chemotherapy Class in High‐Risk Ambulatory Cancer Patients: A Post Hoc Analysis of the AVERT Trial

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in cancer patients. The AVERT trial showed apixaban thromboprophylaxis reduced VTE in intermediate‐to‐high‐risk patients initiating chemotherapy. However, the efficacy and safety of apixaban according to baseline chemotherapy class remain incompletely ...
Nadia Linxi Feng, John Doering, Tzu‐Fei Wang, Ranjeeta Mallick, Grégoire Le Gal, Joseph Shaw, Danny Hill, Sudeep Shivakumar, Vicky Tagalakis, Phil Wells, Marc Carrier   +10 more
wiley   +1 more source

Oral anticoagulation in very elderly patients with atrial fibrillation: Results from the prospective multicenter START2-REGISTER study.

PLoS ONE, 2019
Direct oral anticoagulants (DOACs) have shown similar efficacy and safety with respect to warfarin in patients with atrial fibrillation (AF). However, the proportion of patients aged ≥85 years enrolled in clinical trials was low and the applicability of ...
Daniela Poli, Emilia Antonucci, Walter Ageno, Lorenza Bertù, Ludovica Migliaccio, Lucia Martinese, Giuseppe Pilato, Sophie Testa, Gualtiero Palareti   +8 more
doaj   +1 more source

A Model for Estimating the Risk of Gastrointestinal Bleeding for Patients on Oral Anticoagulants and Interacting Medications

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 11, November 2026.
ABSTRACT Introduction Pharmacodynamic drug–drug interactions (DDI) in patients receiving oral anticoagulants (OAC) may increase the risk of gastrointestinal bleeding (GIB). The purpose of this study was to develop and validate a GIB model for patients receiving OACs.
Ainhoa Gomez‐Lumbreras, Abdelrahman G. Tawfik, Thomas Reese, Daniel M. Witt, Guilherme Del Fiol, Daniel C. Malone   +5 more
wiley   +1 more source

Inside the ‘Black Box’ of Pharmaceuticalisation: NICE, the Permissive Principle and the Case of Anticoagulants

Sociology of Health &Illness, Volume 48, Issue 8, November 2026.
ABSTRACT Sociological interest in pharmaceuticalisation continues to grow, especially regarding the expansion of pharmaceutical use in society. This article presents the first major empirical study focusing on the directionality of pharmaceuticalisation by taking cost‐effectiveness assessment and regulation of anticoagulants in England by the National ...
John Abraham, Gowree Balendran
wiley   +1 more source

Safety of DOACs in patients with Child‐Pugh Class C cirrhosis and atrial fibrillation

JGH Open
Background Anticoagulation (AC) is used for stroke prevention in atrial fibrillation (AF). Direct Oral Anticoagulants (DOACs) are safe in patients with AF without cirrhosis, they are hardly studied in patients with advanced cirrhosis. Our study evaluates
Mark Ayoub, Carol Faris, Julton Tomanguillo Chumbe, Ebubekir Daglilar, Nadeem Anwar, Vishnu Naravadi   +5 more
doaj   +1 more source