Results 81 to 90 of about 5,988 (201)

Evolving Mechanisms on Mortality in Atrial Fibrillation: A 25‐Year National Death‐Certificate Analysis

Journal of Cardiovascular Electrophysiology, EarlyView.
This 25‐year national analysis reveals a major shift in atrial fibrillation‐related mortality, driven by rapidly rising rates of heart failure and stroke‐free dementia. These trends underscore the urgent need to expand management beyond traditional stroke prevention to prioritize comprehensive heart failure care and cognitive health.
Jacqueline S. Dickey, Ashley Goodwin, Bobby Endo, Arthur Chen, Marc C. Engels, Klitos Konstantinidis, Immo Lehmann, Jose Roberto Martinez‐Parachini, Douglas L. Packer, Ravi Ranjan, Benjamin A. Steinberg, T. Jared Bunch   +11 more
wiley   +1 more source

Viscoelastic monitoring of direct oral anticoagulants (DOAC): Viscoeslastic monitoring of DOAC

Blood Transfusion
The management of procedures at risk of major or critical bleeding in patients treated with direct oral anticoagulants (DOAC) is challenging, making urgent monitoring to detect and quantify residual effects, optimal for accurate clinical decision making.
Mora, Lidia, Pons-Pellicé, Laura, Quintana-Díaz, Manuel   +2 more
openaire   +1 more source

The DOAC‐FRAIL Study—Same Dose, Different Story: Prevalence of Deviant Direct Oral Anticoagulant Levels in Nursing Home Residents

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are prescribed using fixed dosing regimens, despite limited evidence on their pharmacokinetic behavior in nursing home residents. Participants and Setting One hundred nursing home residents are receiving apixaban, rivaroxaban, dabigatran, or edoxaban in multiple long‐term care facilities in the ...
Irme S. Franssen, Melanie J. de Jong, Lars Visseren, Daan Teerds, Dave Hellenbrand, Yvonne Henskens, Henri Spronk, Daisy J. A. Janssen, Dionne C. W. Braeken, Sander M. J. van Kuijk, Kristien Winckers, Fabienne J. H. Magdelijns   +11 more
wiley   +1 more source

Direct oral anticoagulants compared with other strategies in patients with atrial fibrillation and stroke or transient ischemic attack: Systematic review

Journal of the Formosan Medical Association
Background: For patients with atrial fibrillation and a prior stroke or transient ischemic attack (TIA), the risk-benefit of direct oral anticoagulants (DOACs) compared to alternative treatment approaches has not been firmly established.
Kuan-Hsin Lee, Wei-Tse Hung, Wen-Yi Huang, Bruce Ovbiagele, Meng Lee   +4 more
doaj   +1 more source

Oral Soft Tissue Biopsy in Patients Receiving Direct Oral Anticoagulants: A Prospective Cohort Study on Bleeding Outcomes

Oral Diseases, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti, Chiara Cinquini, Antonio Barone, Marco Nisi   +3 more
wiley   +1 more source

Warfarin versus DOACs in the prevention of thromboembolic stroke in patients with Afib.

, 2021
Purpose: Preventing thromboembolic (TE) events “such as stroke” is an important part of managing patients with non-valvular atrial fibrillation (Afib). Over the last 50 years, oral anticoagulant treatment with the Vitamin K Antagonist (VKA) warfarin has ...
Szabon, Allen
core   +1 more source

Direct Oral Anticoagulants or Standard Anticoagulant Therapy in Fragile Patients with Venous Thromboembolism

TH Open, 2019
Background The efficacy and safety of the direct oral anticoagulants (DOACs) in fragile patients (age ≥ 75 years and/or creatinine clearance levels ≤ 50 mL/min and/or body weight ≤ 50kg) with venous thromboembolism (VTE) has not been evaluated.
Juan J. López-Núñez, Ricard Pérez-Andrés, Pierpaolo Di Micco, Sebastian Schellong, Covadonga Gómez-Cuervo, Joan Carles Sahuquillo, Maurizio Ciammaichella, Maria del Valle Morales, Marijan Bosevski, Manuel Monreal   +9 more
doaj   +1 more source

Management of Left Atrial Appendage Thrombi and Spontaneous Echo Contrast

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background To analyze the efficacy and safety of various anticoagulation strategies/regimen used for managing thrombus or spontaneous echo contrast in the left atrial appendage. Methods Thrombus or spontaneous echo contrast in the left atrial appendage was detected via transesophageal echocardiography in 83 patients, most often during a stroke
Timnou Bekouti Jean, Ravakiniaina Ranaivosoa Mialy, Ateba Ateba Nelly Stella, Tsague Kegni Hermann, Rambolarimanana Mansh, Ndobo Julia Valérie, Imbey Eheth Levy, Maury Philippe, Diawara Alpha, Roynard Jean Louis, Boombhi Jerome Hilaire   +10 more
wiley   +1 more source

Left Atrial Appendage Occlusion vs Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: A Meta‐Analysis

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Left atrial appendage occlusion (LAAO) has emerged as a non‐pharmacological alternative to oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation (AF). Following the publication of recent CHAMPION‐AF and CLOSURE‐AF trials, an updated synthesis of evidence is warranted to clarify the long‐term ...
Ahmed Nazmy, Alaa Abdrabou Abouelmagd, Ahmed Sobhy, Mennatullah Ashour, Hassan El‐shirbiny, Moneeb Khalaph, Ahmed Yasser Shaban, Mahmoud Nazmy, Amroos Shabaan, Abdullah Farahat Elbanna, Abdelrahman Hafez, C. Michael Gibson   +11 more
wiley   +1 more source

Comparative efficacy and safety of warfarin and direct oral anticoagulants in patients with end-stage kidney disease and atrial fibrillation [PDF]

The Korean Journal of Internal Medicine
Background/Aims Patients with atrial fibrillation (AF) and end-stage kidney disease (ESKD) require careful anticoagulation because thrombotic and bleeding risks are both elevated.
Yujin Yang, Sun Hwa Lee, Wonmook Hwang, Ji Hoon Jung, Jae-Hyeong Park   +4 more
doaj   +1 more source