Results 111 to 120 of about 137,684 (276)

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Advanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo, Grant Phillips, Sriganesh Srihari, Áine Farrell, Binny Jaradi, Kira J. Fitzpatrick, John W. Yaxley, Hemamali Samaratunga, Paul N. Mainwaring, Ke‐lin Ru, Darren J. Korbie, Scott A. Tomlins, Matthew J. Roberts, Robert A. Gardiner, Matt Trau   +14 more
wiley   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

The large D black hole dynamics in AdS/dS backgrounds

, 2018
We have constructed a class of perturbative dynamical black hole solutions in presence of cosmological constant. We have done our calculation in large number of dimensions.
Bhattacharyya, Sayantani, Biswas, Parthajit, Chakrabarty, Bidisha, Dandekar, Yogesh, Dinda, Anirban   +4 more
core   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Probabilistic analysis of stress intensity factor (SIF) and degree of bending (DoB) in axially loaded tubular K-joints of offshore structures

Latin American Journal of Solids and Structures
The stress intensity factor (SIF) and the degree of bending (DoB) are among the crucial parameters in evaluating the fatigue reliability of offshore tubular joints based on the fracture mechanics (FM) approach. The value of SIF is a function of the crack
Hamid Ahmadi, Amirreza Ghaffari
doaj   +1 more source

Missing Persons Bulletin, Iowa Department of Public Safety, January 2001 [PDF]

, 2001
Monthly newsletter for public ...

core  

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

A Finite-Time Disturbance Observer for Tracking Control of Nonlinear Systems Subject to Model Uncertainties and Disturbances

Mathematics
In this study, a finite-time disturbance observer (FTDOB) with a new structure is originally put forward for the motion tracking problem of a class of nonlinear systems subject to model uncertainties and exogenous disturbances.
Manh Hung Nguyen, Kyoung Kwan Ahn
doaj   +1 more source

Toward Complete CO2 Electroconversion: Status, Challenges, and Perspectives

Advanced Energy Materials, EarlyView.
Electrocatalytic CO2 reduction and CO2 batteries face challenges in achieving complete CO2 conversion with high conversion rates and Faradaic efficiency simultaneously. Existing systems compromise one for the other with incomplete CO2 conversion and inefficiencies, hindering practical applications. This perspective highlights state‐of‐the‐art progress,
Changfan Xu, Ping Hong, Yulian Dong, Marc Robert, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

Spartan Daily, October 5, 2004 [PDF]

, 2004
Volume 123, Issue 26https://scholarworks.sjsu.edu/spartandaily/10030/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +3 more sources