Results 221 to 230 of about 137,598 (276)

Optimizing adolescent HIV care: a review of EMR system quality for clinical monitoring in Zambia. [PDF]

Front Public Health
Moomba K, Van Wyk B.
europepmc   +1 more source

Helicobacter pylori infection might be a protective factor against Parkinson's disease. [PDF]

Sci Rep
Xiao X, Wang Z, Zhang H, Li B, Hou Q, Wang J, Xiu W, Zhang R, Zhang G, Lan Y, Chen Y, Zhang M, Sun C, Gao Y, Li A, Zhu X, Gao C, He C, Lu F, Shuai P.   +19 more
europepmc   +1 more source

Projecting the benefit of vericiguat in PARADIGM‐HF and DAPA‐HF populations: Insights from the VICTORIA trial

ESC Heart Failure, Volume 12, Issue 2, Page 1479-1484, April 2025.
Abstract Aims The VICTORIA trial demonstrated a significant reduction in the primary composite outcome of heart failure (HF) hospitalization or cardiovascular death with vericiguat relative to placebo in high‐risk HF. This study aimed to contextualize treatment effects of vericiguat in populations with varying risk profiles simulated from the PARADIGM ...
Veraprapas Kittipibul, Robert J. Mentz, Rebecca Young, Javed Butler, Justin A. Ezekowitz, Carolyn S.P. Lam, Piotr Ponikowski, Adriaan Voors, Stefano Corda, Ciaran McMullan, Christopher M. O'Connor, Kevin J. Anstrom, Paul W. Armstrong, for the VICTORIA Study Group   +13 more
wiley   +1 more source

Mucosal Brush Sampling Increases the <i>Helicobacter pylori</i> Detection Rate of the Rapid Urease Test: A Pilot Study. [PDF]

Gut Liver
Bang CS, Choi AI, Choi JG, Lee JJ, Gong EJ.   +4 more
europepmc   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

β-adrenergic receptor inhibits heart regeneration by downregulating Yap m6A modification. [PDF]

Cell Death Dis
Guan K, Li Z.
europepmc   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

ob/ob obese mice promote tumorigenesis of endometrial cancer associated with Pten deficiency. [PDF]

Endocr Relat Cancer
Kim KC, Hull A, Johannsen E, Hunter MI, Kim TH, Jeong JW.   +5 more
europepmc   +1 more source

Prospective evaluation of a seizure detection wearable device for timely interventions in an epilepsy monitoring unit

Epilepsia, EarlyView.
Abstract Objective This study aimed to evaluate the real‐world performance of a wrist‐worn seizure detection device for timely clinical interventions within an epilepsy monitoring unit (EMU). Methods We conducted a prospective observational study involving patients admitted to the EMU at a tertiary care center.
Amirhossein Jahani, Daniel Alejandro Galindo Lazo, Isabel Sarzo Wabi, Oumayma Gharbi, Manon Robert, Juan Pablo Millan, Gianluca D'onofrio, Alexis Robin, Dang K. Nguyen, Elie Bou Assi   +9 more
wiley   +1 more source

Aspen impedes wildfire spread in southwestern United States landscapes. [PDF]

Ecol Appl
Harris MP, Coop JD, Balik JA, McFarland JR, Parks SA, Stevens-Rumann CS.   +5 more
europepmc   +1 more source