Ribose supplementation alone or with elevated creatine does not preserve high energy nucleotides or cardiac function in the failing mouse heart [PDF]
Background: Reduced levels of creatine and total adenine nucleotides (sum of ATP, ADP and AMP) are hallmarks of chronic heart failure and restoring these pools is predicted to be beneficial by maintaining the diseased heart in a more favourable energy ...
Aksentijevic, Dunja +6 more
core +2 more sources
Comparison of Levosimendan, Milrinone and Dobutamine in treating Low Cardiac Output Syndrome Following Valve Replacement Surgeries with Cardiopulmonary Bypass [PDF]
Introduction: Low Cardiac Output Syndrome (LCOS) following Cardiopulmonary Bypass (CPB) is common and associated with increased mortality. Maintenance of adequate cardiac output is one of the primary objectives in management of such patients. Aim: To
Sunny +5 more
doaj +1 more source
Cardioprotective effects of compound ALM-802 on subendocardial ischemia models
The investigation purpose. N1-(2,3,4-trimethoxybenzyl)-N2-{2-[(2,3,4-trimethoxybenzyl)amino]ethyl}-1,2-ethanediamine (ALM-802 compounds) cardioprotective effect has been studied in rat models of subendocardial ischemia caused by isoproterenol and ...
I. B. Tsorin +5 more
doaj +1 more source
DOBUTAMINE USAGE IN CARDIOLOGICAL PRACTICE
Dobutamine is inotropic drug indicated in systolic dysfunction. Data on dobutamine pharmacology, its effects on hemodynamics, coronary and peripheral blood flow, myocardial electrophysiology are presented. Clinical usage and the main contraindications of
M. Yu. Giljarov
doaj +1 more source
Purpose: Ocular blood flow (OBF) is an important risk factor for incidence, prevalence and progression of some ocular disorders. To date, there are very limited therapeutic options to increase OBF.
Linkun Cai +11 more
doaj +1 more source
Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI) [PDF]
Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling.
Aicher, A +12 more
core +1 more source
Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core +2 more sources
Background Detection of flow reserve (FR) by dobutamine stress echocardiography is used for risk stratification in low‐gradient aortic stenosis (AS).
Kimi Sato +13 more
semanticscholar +1 more source
Effects of Vasoactive Drug Use on Hemodynamics in Critical Disease Pediatic Patients
Introduction:The fact that critically ill pediatric patients have hemodynamic and metabolic characteristics different from that in adults plays a key role in the selection of vasoactive agent.
Melike Ersoy, Metin Karaböcüoğlu
doaj +1 more source
What role does the right side of the heart play in circulation? [PDF]
Right ventricular failure (RVF) is an underestimated problem in intensive care. This review explores the physiology and pathophysiology of right ventricular function and the pulmonary circulation.
Cecconi, M, Johnston, E, Rhodes, A
core +2 more sources

