Results 1 to 10 of about 9,011 (201)
New England Journal of Medicine, 2017 Commentum to "Levosimendan for the Prevention of Acute Organ Dysfunction in ...
Alessandro Belletti, Mervyn Singer
exaly +15 more sources
Clinical Characteristics and Outcomes of 1894 Women with Peripartum Cardiomyopathy Treated with and Without Levosimendan in Germany [PDF]
Journal of Cardiovascular Development and DiseaseBackground: Peripartum cardiomyopathy (PPCM) is a rare form of heart failure occurring during the last month of pregnancy or within five months postpartum.
Jan A. Kloka +9 more
doaj +2 more sources
Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis [PDF]
New England Journal of Medicine, 2016 BACKGROUND Levosimendan is a calcium-sensitizing drug with inotropic and other properties that may improve outcomes in patients with sepsis. METHODS We conducted a double-blind, randomized clinical trial to investigate whether levosimendan reduces the ...
Gavin D Perkins, Frcp, Fficm +2 more
exaly +4 more sources
Levosimendan: a cardiovascular drug to prevent liver ischemia-reperfusion injury? [PDF]
PLoS ONE, 2013 INTRODUCTION: Temporary occlusion of the hepatoduodenal ligament leads to an ischemic-reperfusion (IR) injury in the liver. Levosimendan is a new positive inotropic drug, which induces preconditioning-like adaptive mechanisms due to opening of ...
Peter Onody +11 more
doaj +5 more sources
Effect of levosimendan treatment in cardiac surgery: a network meta-analysis of randomized controlled trials [PDF]
Frontiers in Cardiovascular MedicineBackgroundThe prophylactic administration of levosimendan in patients undergoing cardiac surgery remains clinically contentious, particularly regarding its efficacy and safety in improving key postoperative outcomes, such as cardiac function, renal ...
Binlu Zhu, Wanling Zhao, Yifei Li
doaj +2 more sources
The Effects of Levosimendan on Microcirculation and Peripheral Perfusion in Septic Shock: A Pilot Study [PDF]
LifeSeptic patients can show multiorgan failure even after an apparent recovery of hemodynamic stability. The underlying mechanism is unclear, but the main pathological element is microcirculation impairment, leading to insufficient oxygen delivery.
Veronica Gagliardi +3 more
doaj +2 more sources
Journal of Cardiovascular Development and Disease, 2022 (1) Background: The present study aims to investigate the effect of administration of Levosimendan and Exenatide in various concentrations, as well as of the coadministration of those agents in an ischemia–reperfusion injury isolated heart model.
Vasileios Leivaditis +11 more
doaj +1 more source
Prevention of acute kidney injury and protection of renal function in the intensive care unit : update 2017 [PDF]
, 2017 Background: Acute kidney injury (AKI) in the intensive care unit is associated with significant mortality and morbidity. Objectives: To determine and update previous recommendations for the prevention of AKI, specifically the role of fluids, diuretics ...
Druml, W +8 more
core +15 more sources
Indian Heart Journal, 2021 To assess the clinical outcomes of levosimendan and dobutamine in patients with acute decompensated heart failure with reduced ejection fraction and impaired renal function in Indian scenario.
Basil John, Pharm D +4 more
doaj +1 more source
BMC Cardiovascular Disorders, 2022 Background Levosimendan can improve clinical symptoms and the cardiorenal rescue success rate, and stabilize hemodynamic parameters in individuals suffering from acute decompensated heart failure.
Miaomiao Li +5 more
doaj +1 more source