Results 31 to 40 of about 6,285 (202)

Comparison of Levosimendan, Milrinone and Dobutamine in treating Low Cardiac Output Syndrome Following Valve Replacement Surgeries with Cardiopulmonary Bypass [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Low Cardiac Output Syndrome (LCOS) following Cardiopulmonary Bypass (CPB) is common and associated with increased mortality. Maintenance of adequate cardiac output is one of the primary objectives in management of such patients. Aim: To
Sunny, Mohd Yunus, Habib Md Reazaul Karim, Manuj Kumar Saikia, Prithwis Bhattacharyya, Samarjit Dey   +5 more
doaj   +1 more source

Levosimendan in sepsis

, 2020
Levosimendan is a calcium sensitizer and its inotropic effect is mainly attributed to the troponin C of the myocardial fine filaments with calcium. Levosimendan also inhibits phosphodiesterase III. In contrast to inotropic effects, this does not increase
Burcu Tanay Demirdöven, Ugur Koca*
core   +1 more source

Inhaled levosimendan versus intravenous levosimendan in patients with pulmonary hypertension undergoing mitral valve replacement

Annals of Cardiac Anaesthesia, 2018
Context: Inhaled levosimendan may act as selective pulmonary vasodilator and avoid systemic side effects of intravenous levosimendan, which include decrease in systemic vascular resistance (SVR) and systemic hypotension, but with same beneficial effect ...
Tanveer Singh Kundra, P S Nagaraja, K S Bharathi, Parminder Kaur, N Manjunatha   +4 more
doaj   +1 more source

Levosimendan and systemic vascular resistance in cardiac surgery patients: a systematic review and meta-analysis. [PDF]

, 2019
Levosimendan is a potent non-adrenergic inodilator agent. The net effect of hemodynamic changes may result in a hyperdynamic state with low systemic vascular resistance. We conducted a systematic review and meta-analysis assessing hemodynamics in cardiac
Eberle, Balthasar, Carrel, Thierry, Erdös, Gabor, Friess, Jan-Oliver, Heinisch, Paul Philipp, Terbeck, Sandra, Lenz, Armando, Günsch, Dominik   +7 more
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Renal effects of levosimendan: a consensus report. [PDF]

, 2013
Renal dysfunction is common in clinical settings in which cardiac function is compromised such as heart failure, cardiac surgery or sepsis, and is associated with high morbidity and mortality.
Hasslacher J, Morelli A, Oulego Erroz I, Silva Cardoso JC, Treskatsch S, Vrtovec B, le Noble J, Oldner A, Wikström G., Ricksten SE, MORELLI, Andrea, Yilmaz MB, Mebazaa A, Parissis JT, FEDELE, Francesco, Kivikko M, Édes I, GROSSINI, Elena, Salmenperä M, Poelzl G, Rehberg S, Pollesello P, Fedele F, Parkhomenko A, Singer M, Rodríguez Fernández LM, Grossini E, Harjola VP   +27 more
core   +2 more sources

Levosimendan for sepsis-induced myocardial dysfunction: friend or foe?

Frontiers in Cardiovascular Medicine
Sepsis-induced myocardial dysfunction (SIMD) involves reversible myocardial dysfunction. The use of inotropes can restore adequate cardiac output and tissue perfusion, but conventional inotropes, such as dobutamine and adrenaline, have limited efficacy ...
Xinxin Du, Xinxin Du, Fang Xiong, Yafei Hou, Xiangyou Yu, Pengfei Pan   +5 more
doaj   +1 more source

Le lévosimendan en cardiologie et chirurgie cardiaque sous circulation extracorporelle

Avicenna Medical Research, 2023
Introduction : le lévosimendan est un agent inodilatateur utilisé avec succès dans le traitement de l’insuffisance cardiaque aigue et chronique.
Sayad, M Abdelbaki, Mehyaoui
doaj   +1 more source

Two-pronged Strategy for Using DIC to Compare Selection Models with Non-Ignorable Missing Responses [PDF]

, 2012
Data with missing responses generated by a non-ignorable missing-ness mechanism can be analysed by jointly modelling the response and a binary variable indicating whether the response is observed or missing.
Best, Nicky, Richardson, Sylvia, Mason, Alexina   +2 more
core   +1 more source

Levosimendan, a new therapeutic approach to prevent delayed cerebral vasospasm after subarachnoid hemorrhage? [PDF]

, 2016
BACKGROUND Under physiological cerebral conditions, levosimendan, a calcium-channel sensitizer, has a dose-dependent antagonistic effect on prostaglandin F2alpha (PGF)-induced vasoconstriction.
Stefan Wanderer, Konczalla, Juergen, Jan Mrosek, Hartmut Vatter, Mrosek, Jan, Juergen Konczalla, Seifert, Volker, Platz, Johannes, Volker Seifert, Schuss, Patrick, Patrick Schuss, Gueresir, Erdem, Johannes Platz, Wanderer, Stefan, Vatter, Hartmut, Erdem Gueresir   +15 more
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Levosimendan improves cardiac function and myocardial efficiency in rats with right ventricular failure

Pulmonary Circulation, 2017
Levosimendan is an inotropic and vasodilator drug, which is known to improve cardiac function in animal models of right ventricular (RV) failure. The effects of levosimendan on oxygen consumption and myocardial efficiency in the failing RV is unknown. We
Mona S. Hansen, Asger Andersen, Lars P. Tolbod, Nils H. Hansson, Roni Nielsen, Anton Vonk-Noordegraaf, Jens Erik Nielsen-Kudsk   +6 more
doaj   +1 more source