Results 41 to 50 of about 9,011 (201)
Heart failure : studies of prognosis and advanced therapy [PDF]
, 2017 Background Heart failure (HF) is a major health problem affecting 2-3% of the Western population. The clinical syndrome of HF is associated with reduced (HFrEF) or preserved (HFpEF) ejection fraction.
Thorvaldsen, Tonje
core +1 more source
Levosimendan Increases Survival in a D-Galactosamine and Lipopolysaccharide Rat Model
Biomedicines, 2022 Levosimendan, a calcium sensitizer, has an organ protective profile through the inhibition of inflammatory mediators and cytokines in critical conditions, such as heart failure, ischemia-reperfusion injury, and sepsis. The survival effect of levosimendan
Tatsuma Sakaguchi +7 more
doaj +1 more source
Peripartum cardiomyopathy: diagnosis and management [PDF]
, 2017 No abstract ...
Coats, Caroline J. +5 more
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Levosimendan: The current situation and new prospects
Revista Portuguesa de Cardiologia, 2014 Levosimendan is a pyridazinone-dinitrile derivative with positive inotropic and vasodilatory effects that has beneficial effects on myocardial performance.In previous randomized studies levosimendan improved hemodynamics and clinical course, but its ...
Nuno Moreno +5 more
doaj +1 more source
Pulmonary Circulation, 2017 Levosimendan is an inotropic and vasodilator drug, which is known to improve cardiac function in animal models of right ventricular (RV) failure. The effects of levosimendan on oxygen consumption and myocardial efficiency in the failing RV is unknown. We
Mona S. Hansen +6 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: Aortic stenosis (AS) increases left ventricular afterload, leading to cardiac damage and heart failure (HF). Transcatheter aortic valve replacement (TAVR) is an effective therapy for AS.
Zhenyan Zhao +12 more
doaj +1 more source
Cardiovascular drug therapy for human newborn: review of pharmacodynamic data [PDF]
, 2017 BACKGROUND: Circulatory failure in preterm and term newborn infants is commonly treated with inotropes or vasoactive medications. In this structured literature review, the available data on pharmacodynamic effects of the inotropes adrenaline ...
Bravo, MC +5 more
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ESC Heart Failure, Volume 12, Issue 2, Page 1336-1345, April 2025.Abstract Aims Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was to investigate in‐hospital prognosis and mortality in CS patients according to aetiology. We also assessed the prognostic accuracy of CardShock and IABP‐SHOCK II scores.
Cosme García‐García +17 more
wiley +1 more source
Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial
ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad +9 more
wiley +1 more source
Use of Levosimendan in Cardiac Anesthesiology
Общая реаниматология, 2011 The authors consider the main aspects of the rational use of the novel inotropic drug levosimendan in cardiosurgical patients on the basis of the results of the trials described in the literature and on their own findings in this review.
L. A. Krichevsky +4 more
doaj +1 more source