Results 61 to 70 of about 3,878 (166)

Revealing the Hidden Severity: A Case Report on Managing Complex Aortic Stenosis With TAVI

Case Reports in Cardiology, Volume 2026, Issue 1, 2026.
Aortic stenosis (AS) is a progressive condition prevalent in older adults, with severity determined through clinical evaluation and imaging. However, diagnostic dilemmas arise when imaging results conflict with clinical symptoms. This report examines an 84‐year‐old male with chronic kidney disease, prior abdominal aortic aneurysm repair and other ...
Thomas Stefoulis, James Sindone, Mahiar Mahjoub, Samuel Jay-Jackson Pack, Sean Lal, Satabdi Datta Choudhury   +5 more
wiley   +1 more source

The therapeutic effect of levosimendan in patients with prolonged ventilator weaning and cardiac dysfunction

Journal of International Medical Research
Objective To explore the therapeutic effect of levosimendan in patients with prolonged ventilator weaning and cardiac dysfunction. Method Patients with prolonged ventilator weaning and cardiac dysfunction were randomly allocated to receive conventional ...
Fang Xiong, Zongjun Hu, Chao Liu, Kexiang Zhang, Qilong Zhou, Jianguo Chen, Hua Lu, Xi Yue, Jianxin Zhao, Pengfei Pan   +9 more
doaj   +1 more source

Reuse of a Previously Transplanted Heart

Case Reports in Transplantation, Volume 2026, Issue 1, 2026.
Heart transplantation remains the gold standard treatment for end‐stage heart failure. However, the persistent shortage of donor organs continues to limit the number of procedures performed worldwide. Several strategies have been developed to expand the donor pool, including the reuse of a previously transplanted cardiac graft, which represents a rare ...
Alexis Krin, Myriam Addi, Jean Porterie, Evaldo Favi   +3 more
wiley   +1 more source

Prophylactic use of levosimendan in pediatric patients undergoing cardiac surgery: a prospective randomized controlled trial

Critical Care, 2019
Background The administration of levosimendan prophylactically to patients undergoing cardiac surgery remains a controversial practice, and few studies have specifically assessed the value of this approach in pediatric patients.
Anbiao Wang, Chaomei Cui, Yiou Fan, Jie Zi, Jie Zhang, Guanglai Wang, Fang Wang, Jun Wang, Qi Tan   +8 more
doaj   +1 more source

Effect of levosimendan, a calcium sensitizer, on cisplatin-induced nephrotoxicity in rats

Toxicology Reports, 2019
We investigated the effect of levosimendan on cisplatin (Cis)-induced nephrotoxicity. Rats were divided into four groups (n = 6). The first and second groups received normal saline (control) and intraperitoneal (i.p.) cisplatin (6 mg/kg) on day 7 ...
Aly M. Abdelrahman, Yousuf Al Suleimani, Asem Shalaby, Mohammed Ashique, Priyadarsini Manoj, Hasna Al-Saadi, Badreldin H. Ali   +6 more
doaj   +1 more source

Development and Interpretation of a Machine Learning Model for the Early Prediction of Sepsis‐Induced Cardiomyopathy in Critically Ill Patients

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Background Sepsis‐induced cardiomyopathy (SIC) is a severe complication of sepsis associated with increased mortality, yet early prediction remains a clinical challenge. Machine learning models offer promise for early risk stratification, but their “black‐box” nature limits clinical adoption.
Zhuan Yan, Qingsong Sun, Weiqin Wu, Lili Gao, Liang Chen, Bing Niu   +5 more
wiley   +1 more source

Impact of levosimendan on weaning from peripheral venoarterial extracorporeal membrane oxygenation in intensive care unit

Annals of Intensive Care, 2019
Background Few data are available on the impact of levosimendan in refractory cardiogenic shock patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO). The aim of this study was to evaluate the impact of levosimendan on
Shamir Vally, Cyril Ferdynus, Romain Persichini, Bruno Bouchet, Eric Braunberger, Hugo Lo Pinto, Olivier Martinet, David Vandroux, Thomas Aujoulat, Jérôme Allyn, Nicolas Allou   +10 more
doaj   +1 more source

Levosimendan is superior to epinephrine on coronary flow for lipid-base resuscitation of bupivacaine-induced asystole in the isolated rat heart

BMC Anesthesiology, 2018
Background Successful resuscitation from asystole induced by bupivacaine requires the reestablishment of a sufficient coronary flow (CF) quickly. This study was designed to test whether levosimendan was superior to epinephrine in the reestablishment of ...
Hongfei Chen, Fangfang Xia, Zhousheng Jin, Kejian Shi, Yun Xia, Le Liu, Thomas J. Papadimos, Xuzhong Xu, Limei Chen   +8 more
doaj   +1 more source

Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT

Efficacy and Mechanism Evaluation, 2018
Background: In septic shock, cardiovascular resuscitation using catecholamine vasopressors and inotropes is standard therapy, but catecholamines have important side effects.
Anthony C Gordon, Shalini Santhakumaran, Farah Al-Beidh, Robert ML Orme, Gavin D Perkins, Mervyn Singer, Daniel F McAuley, Alexina J Mason, Josie K Ward, Kieran P O’Dea, Timothy Felton, Mary Cross, Janis Best-Lane, Jonas Lexow, Ashley Campbell, Deborah Ashby   +15 more
doaj   +1 more source

Repeated levosimendan administration guided by invasive hemodynamic assessment in postcardiotomy cardiogenic shock after off-pump coronary artery bypass grafting: a case report

Journal of Cardiothoracic Surgery
Postcardiotomy cardiogenic shock is a life-threatening complication after coronary artery bypass grafting (CABG), especially in patients with severely impaired left ventricular systolic function.
Oleg Kuntsevich, Nikita Chibisov, Dmitry Levikov, Evgeny Rodionov   +3 more
doaj   +1 more source