Results 61 to 70 of about 9,011 (201)

Levosimendan, a Promising Pharmacotherapy in Cardiogenic Shock: A Comprehensive Review

European Cardiology Review
Cardiogenic shock (CS) is a critical condition with high mortality rate, as the current management of CS presents significant challenges. Exploration of more effective therapies is necessitated.
Hendri Susilo, Fan Maitri Aldian, Citrawati Dyah Kencono Wungu, Mochamad Yusuf Alsagaff, Henry Sutanto, Chaq El Chaq Zamzam Multazam   +5 more
doaj   +1 more source

Effect of levosimendan infusion prior to left ventricular assist device implantation on right ventricular failure

Journal of Cardiothoracic Surgery, 2022
Objective Investigate the safety and efficacy of preoperative levosimendan in patients undergoing left ventricular assist device (LVAD) implantation.
Amitai Segev, Jacob Lavee, Yigal Kassif, Yedida Shemesh, Alexander Kogan, Dov Freimark, Avi Morgan, Dor Lotan, Edward Itelman, Avishay Grupper   +9 more
doaj   +1 more source

Practical considerations for the use of vericiguat in older patients with heart failure and reduced ejection fraction

European Journal of Clinical Investigation, Volume 56, Issue 2, February 2026.
Vericiguat represents an optimal therapeutic option for older patients with heart failure with reduced ejection fraction (HFrEF). It possesses several advantages: once daily dosing, favourable tolerability, reassuring safety and limited drug–drug interactions.
Francesco Castelletti, Elena Bianco, Giulia Fabro, Eleonora Nicolini, Francesco Dentali, Luca Liberale, Flavio Tangianu, Aldo Bonaventura   +7 more
wiley   +1 more source

Hemodynamic‐Driven Staging of Heart Failure With Preserved Ejection Fraction Using Unsupervised Cluster Analysis

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Invasive exercise hemodynamics are used to diagnose heart failure with preserved ejection fraction (HFpEF), based on pulmonary artery wedge pressure (PAWP) or left atrial (LA) pressure elevations. We hypothesized that applying unsupervised cluster analysis to comprehensive hemodynamic characterization might provide data‐driven phenotypes, with
Sergio Caravita, Claudia Baratto, Céline Dewachter, Veraprapas Kittipibul, Giovanni Battista Perego, Fabio Previdi, Stefano Paleari, Mattia Cattaneo, Luigi P. Badano, Michele Senni, Marat Fudim, Gianfranco Parati, Jean‐Luc Vachiéry, Ettore Lanzarone   +13 more
wiley   +1 more source

Current state of knowledge on Takotsubo Syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology [PDF]

, 2015
Takotsubo syndrome is an acute reversible heart failure syndrome that is increasingly recognized in modern cardiology practice. This Position Statement from the European Society of Cardiology Heart Failure Association provides a comprehensive review of ...
Akashi, YJ, Bossone, E, Citro, R, Figtree, GA, Filippatos, G, Lyon, A, Mebazaa, A, Omerovic, E, Parodi, G, Ruschitzka, F, Schneider, B, Sechtem, U, Sheppard, MN, Underwood, SR   +13 more
core   +2 more sources

İleri kalp yetersizliği hastalarında levosimendanın eritrosit dağılım genişliği üzerine etkisi

Genel Tıp Dergisi, 2015
Amaç: Levosimendan dekompanse kalp yetersizliğinde kullanılan, olumlu hemodinamik etkileri de olan pozitif inotropik bir ilaçtır. Bu çalışmanın amacı levosimendan tedavisi almış ileri kalp yetersizliği hastalarının tedavi öncesi ve sonrası eritrosit ...
Ahmet Gürel, Niyazi Güler, Murat Aydın, Şeref Alpsoy, Aydın Akyüz, Dursun Çayan Akkoyun   +5 more
doaj  

Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis

Annals of Intensive Care
Background Preliminary evidence from small, single-center studies suggests levosimendan may improve the likelihood of successful venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in patients with cardiogenic shock.
Nicolas Paulo, Antoine Kimmoun, David Hajage, Pierre Hubert, David Levy, Marc Pineton de Chambrun, Juliette Chommeloux, Ouriel Saura, Grégoire Del Marmol, Quentin Moyon, Guillaume Hékimian, Melchior Gautier, Charles Edouard Luyt, Guillaume Lebreton, Bruno Levy, Alain Combes, Matthieu Schmidt   +16 more
doaj   +1 more source

Interpretable Machine Learning Model for Predicting 30‐Day Readmission in Advanced Heart Failure Patients: Synergistic Assessment of Inflammatory and Metabolic Biomarkers

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Background Patients with advanced heart failure (AdHF) face a high risk of early readmission, leading to poor outcomes and increased healthcare burden. Early identification of high‐risk individuals remains a clinical challenge. Methods This retrospective study included 769 AdHF patients from the Affiliated Hospital of Xuzhou Medical University, with an
Baohe Zang, Chengyu Li, Min Zhou, Yali Chao, Irfan Ahmad   +4 more
wiley   +1 more source

Levosimendan as a new force in the treatment of sepsis-induced cardiomyopathy: mechanism and clinical application

Journal of International Medical Research, 2019
The heart is one of the organs most vulnerable to sepsis. This review describes the general characteristics of sepsis-induced cardiomyopathy and the main pathogenesis of myocardial dysfunction in sepsis.
Fei Yang, Li Na Zhao, Yi Sun, Zhuang Chen   +3 more
doaj   +1 more source

Effect of levosimendan, a calcium sensitizer, on cisplatin-induced nephrotoxicity in rats

Toxicology Reports, 2019
We investigated the effect of levosimendan on cisplatin (Cis)-induced nephrotoxicity. Rats were divided into four groups (n = 6). The first and second groups received normal saline (control) and intraperitoneal (i.p.) cisplatin (6 mg/kg) on day 7 ...
Aly M. Abdelrahman, Yousuf Al Suleimani, Asem Shalaby, Mohammed Ashique, Priyadarsini Manoj, Hasna Al-Saadi, Badreldin H. Ali   +6 more
doaj   +1 more source