Results 1 to 10 of about 326 (81)

Levosimendan vs. Intra-Aortic Balloon Pump in Coronary Artery Bypass Grafting: A Meta-Analysis [PDF]

Brazilian Journal of Cardiovascular Surgery
Objective: To compare the clinical efficacy and safety of intra-aortic balloon pump (IABP) and levosimendan in coronary artery bypass grafting (CABG). Methods: A systematic search of PubMed®, Embase, Cochrane Library, and Google Scholar was conducted ...
Yanjie Wang, Jinluan Qu, Dan Sheng, Xiang Sun, Liqin Zhong, Yingjie Wu, Hao Liang   +6 more
doaj   +3 more sources

Efficacy and safety of levosimendan in patients with sepsis: a systematic review and network meta-analysis [PDF]

Frontiers in Pharmacology
Objective: We conducted a systematic review to assess the advantages and disadvantages of levosimendan in patients with sepsis compared with placebo, milrinone, and dobutamine and to explore the clinical efficacy of different concentrations of ...
Ruimin Tan, Ruimin Tan, He Guo, He Guo, Zinan Yang, Zinan Yang, Huihui Yang, Huihui Yang, Qinghao Li, Qinghao Li, Qiong Zhu, Quansheng Du   +11 more
doaj   +2 more sources

Levosimendán preoperatorio en cirugía coronaria con disfunción ventricular severa: ¿tiene sentido?

Cirugía Cardiovascular, 2021
Resumen: Introducción y objetivos: Numerosos estudios han demostrado los beneficios del levosimendán en pacientes con insuficiencia cardiaca crónica y aguda; sin embargo, los resultados son contradictorios cuando se analiza el uso de levosimendán previo
Elena Roselló-Díez, Eduardo Astrosa, Sandra Casellas, Manel Tauron, Josefina Galán, Antonino Ginel, José Montiel   +6 more
doaj   +1 more source

The effect of post-reperfusion levosimendan in an experimental intestinal ischemia–reperfusion model

Journal of Anesthesia, Analgesia and Critical Care, 2022
Background Levosimendan has been reported to have a positive effect on ischemia–reperfusion injury. Herein, we aimed to evaluate the effects of levosimendan applied after reperfusion in an experimental intestinal injury-reperfusion (IR) model.
Hakan Aygun, Cimen Olguner, Ugur Koca, Bekir Ugur Ergur, Ali Rıza Sisman, Duyguhan Isguven, Pelin Girgin, Muhammed Akkus, Serkan Tulgar   +8 more
doaj   +1 more source

Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery: An Update Meta‐Analysis and Trial Sequential Analysis

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Background. Recent studies suggest that levosimendan does not provide mortality benefit in patients with low cardiac output syndrome undergoing cardiac surgery. These results conflict with previous findings. The aim of the current study is to assess whether levosimendan reduces postoperative mortality in patients with impaired left ventricular function
Benji Wang, Xiaojie He, Yuqiang Gong, Bihuan Cheng, Gianluca Pontone   +4 more
wiley   +1 more source

The efficacy of simendan in the treatment of acute heart failure and its impact on NT-proBNP.

European review for medical and pharmacological sciences, 2019
Simendan is a calcium sensitizer that enhances myocardial contractility but does not affect ventricular diastole. Simendan also has a vasodilatation effect, which causes coronary artery resistance and venous volume blood vessel relax, thereby improving coronary blood supply.
Li, J., Wang, X.-Y., Yang, Z.-Y., Li, Y., Yang, F., Yuan, P., Yang, J.   +6 more
openaire   +2 more sources

Therapeutic Development of Levosimendan in Acute and Advanced Heart Failure: A Systematic Review. [PDF]

Cureus, 2023
Desai HN, Sangurima L, Malik MM, Ganatra N, Siby R, Kumar S, Khan S, Jayaprakasan SK, Cheriachan D, Mohammed L.   +9 more
europepmc   +1 more source

Adrenergic Shock Presenting with Atypical Takotsubo Syndrome: The Alliance Between Levosimendan and Intraaortic Balloon Pump Against the Pheochromocytoma. [PDF]

Anatol J Cardiol, 2022
Vincenza Polito M, De Angelis E, Hagendorff A, Puzziello A, Vigorito F, Ravera A.   +5 more
europepmc   +1 more source

Pharmacological regulation of inducible nitric oxide synthase expression. Effects of Janus kinase inhibitors, orazipone and simendans

, 2012
Inflammation is a defence mechanism by which an organism reacts to pathogens and tissue damage. Activated inflammatory cells produce signalling molecules that modulate the inflammatory response and the progress of inflammation. The inflammatory response is usually beneficial and required for survival, but when inappropriately focused or regulated, or ...
openaire   +1 more source

Levosimendan in Right Ventricular Dysfunction. [PDF]

Ann Card Anaesth, 2023
Kapoor MC.
europepmc   +1 more source