Results 71 to 80 of about 9,011 (201)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background This study investigated whether levosimendan, an inotropic calcium sensitizer, when combined with moderate therapeutic hypothermia, may exert synergistic benefits on post–cardiac arrest myocardial dysfunction and improve outcomes.
Chih‐Hung Wang +4 more
doaj +1 more source
Inhibition of reverse-mode sodium-calcium exchanger activity and apoptosis by levosimendan in human cardiomyocyte progenitor cell-derived cardiomyocytes after anoxia and reoxygenation. [PDF]
PLoS ONE, 2014 Levosimendan, a known calcium sensitizer with positive inotropic and vasodilating properties, might also be cardioprotective during ischemia-reperfusion (I/R) insult. Its effects on calcium homeostasis and apoptosis in I/R injury remain unclear. Na(+)/Ca(
Ping-Chun Li +4 more
doaj +1 more source
Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.Background In cardiogenic shock (CS), titration of both the choice and dosage of inotropes and vasopressors is crucial. The vasoactive–inotropic score (VIS) quantifies hemodynamic support, while the effect of temporal VIS change on prognosis remains unclear. This study evaluated the association between the vasoactive–inotropic score reduction rate (VRR)
Yi-Le Ning +9 more
wiley +1 more source
Annals of Intensive Care, 2019 Background Few data are available on the impact of levosimendan in refractory cardiogenic shock patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO). The aim of this study was to evaluate the impact of levosimendan on
Shamir Vally +10 more
doaj +1 more source
Scientific Reports, 2021 Levosimendan and dobutamine are extensively used to treat sepsis-associated cardiovascular failure in ICU. Nevertheless, the role and mechanism of levosimendan in patients with sepsis-induced cardiomyopathy remains unclear.
Dong-Hua Liu +8 more
doaj +1 more source
, 2008 The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008.
Ravi Iyengar
core +2 more sources
Calcium sensitizers: What have we learned over the last 25years? [PDF]
, 2018 K
Papp, Gy. Julius +2 more
core +1 more source
Clinical Case Reports, Volume 13, Issue 12, December 2025.Mitral anterolateral papillary muscle rupture with partial valve body prolapse and severe mitral regurgitation after acute myocardial infarction (ultrasound schematic). ABSTRACT Due to dual blood supply, ischemic mitral anterolateral papillary muscle rupture is less common than that of posteromedial papillary muscle and is rare in acute myocardial ...
Zeyan Liu +4 more
wiley +1 more source
Critical Care, 2019 Background The administration of levosimendan prophylactically to patients undergoing cardiac surgery remains a controversial practice, and few studies have specifically assessed the value of this approach in pediatric patients.
Anbiao Wang +8 more
doaj +1 more source
BMC Anesthesiology, 2018 Background Successful resuscitation from asystole induced by bupivacaine requires the reestablishment of a sufficient coronary flow (CF) quickly. This study was designed to test whether levosimendan was superior to epinephrine in the reestablishment of ...
Hongfei Chen +8 more
doaj +1 more source