Results 71 to 80 of about 3,869 (167)

An In Vitro Investigation of the Antiproliferative and Antimetastatic Effects of Levosimendan: Potential Drug Repurposing for Cervical Cancer

Current Issues in Molecular Biology
Cervical cancer presents a significant challenge to the global health of women. Despite substantial advances in human papillomavirus (HPV)-related cervical cancer vaccines, non-HPV-related cervical cancer is still waiting novel therapeutic options.
Zsuzsanna Schelz, Hiba F. Muddather, Fatemeh Sheihaki Jaski, Noémi Bózsity, István Zupkó   +4 more
doaj   +1 more source

Transdermal delivery of levosimendan

European Journal of Pharmaceutical Sciences, 2000
The aim of this study was to determine if transdermal penetration of levosimendan, a novel positive inotropic drug, could be enhanced and controlled by formulation modifications. Penetration of levosimendan across human epidermis in vitro was determined using abdominal excised skin and diffusion cells.
R, Valjakka-Koskela, J, Hirvonen, J, Mönkkönen, J, Kiesvaara, S, Antila, L, Lehtonen, A, Urtti   +6 more
openaire   +2 more sources

Levosimendan as rescue therapy in low output syndrome after cardiac surgery: effects and predictors of outcome

Journal of International Medical Research, 2019
Objectives Calcium sensitizers have been shown to improve outcomes in patients with low cardiac output syndrome (LCOS) after cardiac surgery. We assessed the effects of levosimendan on LCOS in cardiac surgical patients to identify outcome predictors ...
Andres Beiras-Fernandez, Angela Kornberger, Martin Oberhoffer, Felix Kur, Marion Weis, Christian-Friedrich Vahl, Florian Weis   +6 more
doaj   +1 more source

Bibliometric analysis of levosimendan

IJC Heart & Vasculature
Levosimendan (LEVO), a calcium sensitizer and adenosine triphosphate-dependent potassium channel opener, has been widely used for decades in medical and surgical patients for advanced heart failure (HF), right ventricular failure, cardiogenic shock, takotsubo cardiomyopathy, pulmonary hypertension, and so on. Currently, as the limited scope and lack of
Xian-Shu Zhao, Yi-Ping Yu, Yun-Tai Yao
openaire   +3 more sources

Possibilities of using levosimendan in patients with idiopathic pulmonary hypertension

Терапевтический архив, 2012
Aim. To evaluate the efficiency and safety of intravenous infusion of levosimendan in patients with idiopathic pulmonary hypertension (IPH) and its clinical, hemodynamic, and neurohumoral effects. Subjects and methods. The study included 9 patients (mean
T V Martyniuk, O A Arkhipova, E A Kobal', N M Danilov, I E Chazova   +4 more
doaj  

Levosimendan.

Indian pediatrics, 2010
Shrishu R, Kamath, Indira, Jaykumar, Sunit, Matha   +2 more
openaire   +3 more sources

The case for levosimendan

Critical Care and Resuscitation, 2008
openaire   +2 more sources

Drug sequestration and metabolite formation: key pharmacokinetic challenges for levosimendan use during ECMO support in cardiogenic shock. [PDF]

J Intensive Care
Tebib N, Liaudet L, Ltaief Z.
europepmc   +1 more source

Levosimendan vs. Intra-Aortic Balloon Pump in Coronary Artery Bypass Grafting: A Meta-Analysis. [PDF]

Braz J Cardiovasc Surg
Wang Y, Qu J, Sheng D, Sun X, Zhong L, Wu Y, Liang H.   +6 more
europepmc   +1 more source

Successful use of levosimendan in managing refractory coronary vasospasm leading to recurrent cardiac arrests: a case report. [PDF]

Eur Heart J Case Rep
Ralota KK, Wang W, Layland J.
europepmc   +1 more source