Results 91 to 100 of about 27,276 (262)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
GMOD/docker-apollo: 2.2.0 Release
, 2019 :whale: Apollo 2.X Docker ...
Helena Rasche +2 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Jurnal SaintekomDowntime during deployment remains a major challenge that can disrupt service availability and reduce user trust in websites. This study aims to implement and evaluate the effectiveness of a blue-green deployment strategy based on containerization to ...
Restu Bumi Ryan Ramadhan +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
IEEE AccessA microservice architecture enables the decomposition of applications into loosely coupled and independently deployable components, each responsible for a specific function or service.
Alex Mwotil +2 more
doaj +1 more source
Optimization problems running MPI-based HPC applications
Труды Института системного программирования РАН, 2018 MPI is a well-proven technology that is widely used in a high-performance computing environment. However, configuring an MPI cluster can be a difficult task.
D. A. Grushin, N. N. Kuzjurin
doaj +1 more source
osirrc/jassv2-docker: JASSv2 Docker Image for OSIRRC at SIGIR 2019 (v0.1.1)
, 2019 OSIRRC Docker Image for ...
andrewtrotman, Jimmy Lin, Ryan Clancy
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source