Results 71 to 80 of about 58,341 (324)

Monolithic simulation of convection-coupled phase-change - verification and reproducibility

, 2018
Phase interfaces in melting and solidification processes are strongly affected by the presence of convection in the liquid. One way of modeling their transient evolution is to couple an incompressible flow model to an energy balance in enthalpy ...
C Boettiger, DW Kelly, F Brezzi, GK Batchelor, HW Hsu, I Danaila, J Donea, J Kowalski, MS Dinniman, S Wang, UKNG Ghia, V Alexiades, VR Voller, VR Voller, W Bangerth, Y Belhamadia, Y Dutil   +16 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Virtualization on Internet of Things Edge Devices With Container Technologies: A Performance Evaluation

IEEE Access, 2017
Lightweight virtualization technologies have revolutionized the world of software development by introducing flexibility and innovation to this domain.
Roberto Morabito
doaj   +1 more source

ClouNS - A Cloud-native Application Reference Model for Enterprise Architects

, 2017
The capability to operate cloud-native applications can generate enormous business growth and value. But enterprise architects should be aware that cloud-native applications are vulnerable to vendor lock-in.
Kratzke, Nane, Peinl, René
core   +1 more source

Analysis of Docker Security

CoRR, 2015
Over the last few years, the use of virtualization technologies has increased dramatically. This makes the demand for efficient and secure virtualization solutions become more obvious. Container-based virtualization and hypervisor-based virtualization are two main types of virtualization technologies that have emerged to the market.
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

CREDO: a friendly Customizable, REproducible, DOcker file generator for bioinformatics applications

BMC Bioinformatics
Background The analysis of large and complex biological datasets in bioinformatics poses a significant challenge to achieving reproducible research outcomes due to inconsistencies and the lack of standardization in the analysis process.
Simone Alessandri, Maria L. Ratto, Sergio Rabellino, Gabriele Piacenti, Sandro Gepiro Contaldo, Simone Pernice, Marco Beccuti, Raffaele A. Calogero, Luca Alessandri   +8 more
doaj   +1 more source

DOCKER AND GOOGLE KUBERNETICS.

International Journal of Advanced Research, 2018
In today?s world, every customer is thinking of agility, parallel development and reducing cost, especially infrastructure cost and operational cost. We have seen SOA world where we have written code and multiple services talk to each other?s for a business use case, but sometimes we end up with one big code base which is monolithic in nature and ...
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source