Results 71 to 80 of about 53,480 (280)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The development of an autonomous rendezvous and docking simulation using rapid integration and prototyping technology [PDF]

A generic planar 3 degree of freedom simulation was developed that supports hardware in the loop simulations, guidance and control analysis, and can directly generate flight software.
Adler, James, Saugen, John D., Shackelford, John H., Wurst, Michael J.   +3 more
core   +1 more source

N-Docker: A NVM-HDD Hybrid Docker Storage Framework to Improve Docker Performance

, 2019
Docker has been widely adopted in production environment, but unfortunately deployment and cold-start of container are limited by the low speed of disk. The emerging non-volatile memory (NVM) technology, which has high speed and can store data permanently, brings a new chance to accelerate the deployment and cold-start of container.
Gu, Lin, Tang, Qizhi, Wu, Song, Jin, Hai, Zhang, Yingxi, Shi, Guoqiang, Lin, Tingyu, Rao, Jia   +7 more
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Docker network topologies: Analysis of Bridge, Overlay, and MacvLAN modes [PDF]

Tehnika
In modern container technologies, Docker is a key tool for deploying and managing applications. Understanding the performance of different Docker networking modes is crucial for efficient system design.
Stanišić Sava, Đorđević Borislav, Tot Ivan A., Ristić Olga   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Implementación de contenedores dockers en la enseñanza en línea de Ambientes virtualizados

Programación Matemática y Software, 2022
La enseñanza de ambientes y escenarios virtualizados en las universidades, es un tema que se complica en la modalidad en línea por su naturaleza práctica, compleja y que requiere de ciertos requisitos de software y hardware para su implementación, los ...
Jesús Velázquez Macias, Manuel Veyna Lamas, José Alberto Vela Dávila, Claudia Guadalupe Lara Torres, José Antonio González Sáenz   +4 more
doaj  

Analisis Performansi Layanan FTP danVideo Streaming berbasis Network Function Virtualization menggunakan Docker Containers

Jurnal Elkomika, 2018
ABSTRAK Infrastruktur jaringan seperti router, secara tradisional menggunakan hardware yang bersifat proprietary. Teknologi virtualisasi pada fungsi jaringan atau NFV (Network Function Virtualization) membuat layanan ini dapat diimplementasikan sebagai ...
MANZILA IZNIARDI DJOMI, RENDY MUNADI, RIDHA MULDINA NEGARA   +2 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source