Results 91 to 100 of about 138,378 (261)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
agnsal/docker-apaphpy: 23.04.20
, 2020 A docker image with apache, php ...
Agnese Salutari
core +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
bihealth/reev-docker-compose: v0.6.0
<h3>Features</h3> <ul> <li>add celery worker and beat containers (<a href="https://www.github.com/bihealth/reev-docker-compose/issues/38">#38</a>) (<a href="https://www.github.com/bihealth/reev-docker-compose/issues/
varfish-bot +2 more
core +1 more source
wshands/hmmer-docker: HMMER 3.2.1 with Docker and WDL
, 2019 <p>HMMER 3.2.1 with Docker support and with a Workflow Definition Language (WDL) script and test parameter files.</p ...
Walter Shands
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Arquitecura de Servicios con Docker Swarm
, 2021 Application and service containerization is a complicated process because harmony must be found between private interests, scurity and final clients satisfaction. When containerization services already exist on a company but these are out of date and poorly designed the challenge increases enormously because the expected results have to be better than ...
openaire +1 more source
, 2020 Intial beta release of auto-docker ...
Venkat S. Malladi, Jonathan R. Gesell
core +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source