Results 71 to 80 of about 138,378 (261)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

IMPLEMENTASI CLUSTER MANAGEMENT DENGAN DOCKER SWARM PADA APLIKASI WEB

open access: yes, 2019
Server web menjadi bagian penting dari infrastruktur internet saat ini. Sebagian besar server web yang digunakan saat ini masih banyak menggunakan arsitektur single backend server. Permasalahan yang dapat muncul adalah apakah mampu single server tersebut
Triutomo, Thomas Prayudhi - 155410041
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

SENTRIN- Pengembangan Pembagian Beban Kerja Server Cluster Docker Swarm Berbasis Raspberry Dengan Metode Loadbalancer IP HASH Serta Terautomasi Ansible

open access: yesJurnal Teknologi Informasi dan Ilmu Komputer
Perkembangan teknologi saat ini mempercepat penyebaran informasi, hal ini meningkatkan traffic dan tekanan pada infrastruktur. Menghadapi ini, sistem yang reliable, availability, dan maintainability diperlukan.
Fauzan Adzima Tohari   +2 more
doaj   +1 more source

carlesfernandez/docker-pybombs-gnsssdr: v1.0-rel2021.05.07

open access: yes, 2021
docker-pybombs-gnsssdr This is the first release of docker-pybombs-gnsssdr. This repository contains a Dockerfile that creates a Docker image with GNSS-SDR and its dependencies installed via PyBOMBS. This includes GNU Radio and drivers for a wide range
Carles Fernandez
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Alta Disponibilidade em containers Docker por meio do Docker Swarm

open access: yesProfiscientia, 2019
A virtualização é uma tecnologia que proporciona a execução simultânea dedois ou mais sistemas operacionais ou aplicações em uma máquina física. Com avirtualização é possível otimizar o uso dos recursos de uma máquina física por meio dadistribuição desses recursos entre vários usuários ou ambientes.
Filho, Luiz Carlos da Silva   +1 more
openaire   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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