Results 91 to 100 of about 511,020 (304)

Closed-loop autonomous docking system [PDF]

open access: yes, 1992
An autonomous docking system is provided which produces commands for the steering and propulsion system of a chase vehicle used in the docking of that chase vehicle with a target vehicle.
Dabney, Richard W., Howard, Richard T.
core   +1 more source

Hot-spot analysis for drug discovery targeting protein-protein interactions [PDF]

open access: yes, 2018
Introduction: Protein-protein interactions are important for biological processes and pathological situations, and are attractive targets for drug discovery. However, rational drug design targeting protein-protein interactions is still highly challenging.
Fernández-Recio, Juan, Rosell, Mireia
core   +2 more sources

Parallel Electrical Integration of Photo Bio Electrochemical Systems (photo‐BESs): Performance Gains and Load Dependency

open access: yesAdvanced Materials Technologies, EarlyView.
Parallel wiring of bioelectrochemical devices with conventional generators unexpectedly boosts output. A biophotovoltaic paired with a solar cell delivers up to 50% more power at low loads than their separate contributions; a plant microbial fuel cell shows similar current gains.
Valeria Marsaglia   +4 more
wiley   +1 more source

Investigating the Distribution of Intimin and Invasin in Aeromonas hydrophila and Their Role in Host Tissue Attachment

open access: yesBacteria
Background: Aeromonas hydrophila is a key pathogen affecting freshwater fish, including Labeo rohita (rohu), causing significant aquaculture losses. This study explores the role of intimin and invasin, known virulence factors, in A.
Agradip Bhattacharyya   +2 more
doaj   +1 more source

Multimodal Human–Robot Interaction Using Human Pose Estimation and Local Large Language Models

open access: yesAdvanced Robotics Research, EarlyView.
A multimodal human–robot interaction framework integrates human pose estimation (HPE) and a large language model (LLM) for gesture‐ and voice‐based robot control. Speech‐to‐text (STT) enables voice command interpretation, while a safety‐aware arbitration mechanism prioritizes gesture input for rapid intervention.
Nasiru Aboki   +2 more
wiley   +1 more source

Docking system for spacecraft [PDF]

open access: yes
A mechanism is disclosed for the docking of a spacecraft to a space station where a connection for transfer of personnel and equipment is desired. The invention comprises an active docking structure on a spacecraft and a passive docking structure on the ...
Kahn, Jon B.
core   +1 more source

Dynamic testing of docking system hardware [PDF]

open access: yes, 1972
Extensive dynamic testing was conducted to verify the flight readiness of the Apollo docking hardware. Testing was performed on a unique six degree-of-freedom motion simulator controlled by a computer that calculated the associated spacecraft motions ...
Dorland, W. D.
core   +1 more source

The benefits of in silico modeling to identify possible small-molecule drugs and their off-target interactions [PDF]

open access: yes, 2018
Accepted for publication in a future issue of Future Medicinal Chemistry.The research into the use of small molecules as drugs continues to be a key driver in the development of molecular databases, computer-aided drug design software and collaborative ...
Blomberg N   +6 more
core   +2 more sources

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

open access: yesAdvanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai   +15 more
wiley   +1 more source

Structure-Based Design, Virtual Screening, and Discovery of Novel Patulin Derivatives as Biogenic Photosystem II Inhibiting Herbicides

open access: yesPlants
Computer-aided design usually gives inspirations and has become a vital strategy to develop novel pesticides through reconstructing natural lead compounds.
He Wang   +7 more
doaj   +1 more source

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