Results 101 to 110 of about 511,020 (304)
Latching mechanism Patent [PDF]
, 1971 Latch for fastening spacecraft docking ...
Cobin, J. C., Rhodes, L. L.
core +1 more source
Advanced Science, EarlyView.Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
Druggability Analysis of Protein Targets for Drug Discovery to Combat Listeria monocytogenes
MicroorganismsExtensive research has been conducted to identify key proteins governing stress responses, virulence, and antimicrobial resistance, as well as to elucidate their interactions within Listeria monocytogenes.
Robert Hanes, Yanhong Liu, Zuyi Huang
doaj +1 more source
Technical Challenges Associated with In-Air Wingtip Docking of Aircraft in Forward Flight [PDF]
Autonomous in-air wingtip docking of aircraft offers significant opportunity for system level performance gains for numerous aircraft applications. Several of the technical challenges facing wingtip docking of fixed-wing aircraft are addressed in this ...
Busan, Ronald C. +7 more
core +1 more source
Structural Prediction of Protein–Protein Interactions by Docking: Application to Biomedical Problems [PDF]
, 2018 A huge amount of genetic information is available thanks to the recent advances in sequencing technologies and the larger computational capabilities, but the interpretation of such genetic data at phenotypic level remains elusive.
Barradas-Bautista, Didier +3 more
core +2 more sources
QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
Advanced Science, EarlyView.The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Docking structure for spacecraft Patent [PDF]
, 1969 Development and characteristics of docking structure and apparatus for spacecraft ...
Blumrich, J. F.
core +1 more source
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Autonomous prealignment of a docking mechanism [PDF]
Proposed future space exploration, such as lunar and Martian expeditions, will require autonomous docking of space vehicles. One proposed candidate method of autonomous docking utilizes a actively controlled parallel manipulator.
Carroll, Monty B., Thompson, John A.
core +1 more source
ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells
Advanced Science, EarlyView.With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao +16 more
wiley +1 more source