Results 131 to 140 of about 336,807 (309)

Synthesis, biological evaluation, and molecular docking studies of substituted chromone-2-carboxamide derivatives as anti-breast cancer agents

Open Chemistry
Breast cancer is the second leading cause of mortality among women, accounting for 12.5% of all new cancer cases worldwide. By 2030, the estimated number of deaths will escalate to 11.4 million. The research objective is to design and synthesize safe and
Gangapuram Madhavi, Ghaffari Mohammad A., Eyunni Suresh, Mochona Bereket, Redda Kinfe Ken   +4 more
doaj   +1 more source

Other title: Budget Message of Governor Robert B. Docking to the Kansas Legislature

, 1967
application/pdf; "January 31, 1967.
Kansas. Governor (1967-1975 : Docking)
core  

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Bracket Cements

Australasian Orthodontic Journal, 1973
Docking Alan R.
doaj   +1 more source

Other title: Inaugural Address of Governor Robert B. Docking; Other title: Inaugural Address 1969

, 1969
"Presented at Century II Civic Center, Wichita, Kansas, January 13, 1969, 12:00 NOON.
Kansas. Governor (1967-1975 : Docking)
core  

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Other title: Legislative Message and Budget Report Other title: Message of Robert B. Docking to the Kansas Legislature

, 1972
application/pdf; "January 11,1972."; Includes Budget Message and Highlights of the Budget Report for the Fiscal Year ...
Kansas. Governor (1967-1975 : Docking)
core  

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Advanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li, Bolin Li, Yanan Hao, Bo Pang, Pan Li, Chunli Li, Yu Tang   +6 more
wiley   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

A New Contact Dynamics Model Tool for Hardware-In-The-Loop Docking Simulation

, 2012
One of the goals of performing a hardware-in-the-loop (HIL) simulation at the European Proximity Operation simulator (EPOS 2.0) is to simulate on-orbit docking for verification and validation of the docking phase.
Boge, Toralf, Lampariello, Roberto, Zebenay, Melak, Choukroun, Daniel   +3 more
core