Results 181 to 190 of about 293,887 (293)

Old Town and Dock Area: Structural Changes in Ciudad Vieja of Montevideo

, 2008
Mijal Gandelsman-Trier
openalex   +1 more source

In silico docking and drug design of herbal ligands for anticancer property [PDF]

, 2018
Sandeep Waghulde, MK Kale, VR Patil
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TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Table 1_Toxicity mechanism analysis of cGAS-STING-TBK1 signaling pathway small molecule modulator based on network toxicology and molecular docking strategy: quinacrine acetate as an example.xls

Jinchao Zhu (13301229), Qingyuan Lin (13166349), Honglin Zhu (169482), Siqi Xie (6541346), Shengdong Nie (11147020)   +4 more
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DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

Unraveling the mechanisms of nicotine-induced osteoporosis via network toxicology, bioinformatics, and molecular docking. [PDF]

Tob Induc Dis
Xu S, Wang G, Liu J, Zhang X, Dong X, Liang J, Bai T.   +6 more
europepmc   +1 more source

The docking results and interaction of TLR4-MEV (A-B).

Chuang Li (2010226), Yuejie Zhu (3449027), Xingxing Qi (5737181), Zhenglong Chai (22574718), Jiarui Luo (20323176), Kaiyu Shang (19556287), Tingting Tian (2158204), Huidong Shi (103589), Mingzhe Li (281238), Ruixue Xu (776319), Fuling Pu (22574721), Junyu Kuang (22058072), Fengbo Zhang (220275)   +12 more
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Transient Antiskyrmion‐Mediated Topological Transitions in Isotropic Magnets

Advanced Science, EarlyView.
A transient antiskyrmion‐mediated pathway that drives repeated stripe‐to‐skyrmion transitions is revealed, producing a net increase in topological charge in isotropic Dzyaloshinskii–Moriya interaction films. Experiments and simulations identify the antiskyrmion as a metastable excitation, enabling stochastic bitstream generation for probabilistic ...
Bingqian Dai, Tianyi Wang, Albert Lee, Shijie Xu, Zhongjian Bian, Xinyue Zhu, Puyang Huang, Aadi Chaturvedi, Yaochen Li, Yang Cheng, Qingyuan Shu, Haoran He, Hanshen Huang, Lixuan Tai, Kin Wong, Jinbo Yang, Anjan Soumyanarayanan, Zhaochu Luo, Kang L. Wang   +18 more
wiley   +1 more source

Molecular Strategies of Carbohydrate Binding to Intrinsically Disordered Regions in Bacterial Transcription Factors. [PDF]

Int J Mol Sci
Purtov YA, Ozoline ON.
europepmc   +1 more source

Designing Novel Antiviral Peptides Targeting Dengue NS3 Protease Via Long Short-Term Memory Model, Molecular Docking and Molecular Dynamics Simulations

yuan
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