Results 71 to 80 of about 256,731 (319)

Tail biting in pigs: is it possible to rear the heavy pig avoiding tail docking? [PDF]

, 2013
Tail biting in pigs has been identified as a behavioural problem for decades. It has serious consequences for animal welfare and for the income of the farmers The inability to prevent occurrence of this adverse behavior under commercial farm conditions ...
Scollo, A.
core  

Protein-Protein Docking with F2Dock 2.0 and GB-Rerank

, 2013
Rezaul Chowdhury is with UT Austin; Muhibur Rasheed is with UT Austin; Maysam Moussalem is with UT Austin; Donald Keidel is with The Scripps Research Institute; Arthur Olson is with The Scripps Research Institute; Michel Sanner is with The Scripps ...
Maysam Moussalem, Donald Keidel, Chowdhury Rezaul, Olson Arthur, Michel Sanner, Keidel, Donald, Rezaul Chowdhury (385928), Donald Keidel (385930), Muhibur Rasheed (385929), Bajaj Chandrajit, Chowdhury, Rezaul, Michel Sanner (385933), Sanner, Michel, Moussalem, Maysam, Rezaul Chowdhury, Arthur Olson, Rasheed Muhibur, Sanner Michel, Muhibur Rasheed, Bajaj, Chandrajit, Chandrajit Bajaj, Maysam Moussalem (385931), Keidel Donald, Rasheed, Muhibur, Arthur Olson (385932), Olson, Arthur, Chandrajit Bajaj (61229), Moussalem Maysam   +27 more
core   +1 more source

docking studies

, 2008
Citation: 'docking studies' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.DT06958 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Phytochemical Analysis, Network Pharmacology and in Silico Investigations on Anacamptis pyramidalis Tuber Extracts

Molecules, 2020
Anacamptis pyramidalis (L.) Rich. forms part of the Orchidaceae family that is highly valued for its horticultural as well as therapeutic benefits. The present study set out to investigate the inhibitory activity of A.
Mohamad Fawzi Mahomoodally, Marie Carene Nancy Picot-Allain, Gokhan Zengin, Eulogio J. Llorent-Martínez, Hassan H. Abdullah, Gunes Ak, Ismail Senkardes, Annalisa Chiavaroli, Luigi Menghini, Lucia Recinella, Luigi Brunetti, Sheila Leone, Giustino Orlando, Claudio Ferrante   +13 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Noncovalent interactions between hydroxylated polycyclic aromatic hydrocarbon and DNA: Molecular docking and QSAR study

, 2011
Polycyclic aromatic hydrocarbons (PAHs) can be hydroxylated by CYP450-oxidases (1A1 and 1B1 mainly) and may cause DNA damage and cancer. However, the mechanism of such interactions has not been fully understood.
Fei Li, Jianmin Zhao, You, Liping, Xuehua Li, Xiaoli Liu, Liu, Xiaoli, Liping You, Wu, Huifeng, Huifeng Wu, Li, Xuehua, Linbao Zhang, Li, Fei, Zhang, Linbao, Zhao, Jianmin   +13 more
core   +1 more source

Theoretical evaluation of pectin therapeutic potential in relation to degree of methylation [PDF]

Journal of the Serbian Chemical Society
Pectin is the focus of scientific interest due to both its physicochemical and biochemical properties, as well as its non-toxic nature. Methylation of pectin is a natural process that exists as part of the cell wall defence system against various ...
Martinov Nestorov Jelena B., Janjić Goran V., Petković Benazzouz Marija M.   +2 more
doaj   +1 more source

Biological Evaluation and Molecular Docking Studies of Dimethylpyridine Derivatives [PDF]

Molecules, 2019
Cyclooxygenase inhibitors as anti-inflammatory agents can be used in chemoprevention. Many in vitro and in vivo studies on human and animal models have explained the mechanisms of the chemopreventive effect of COX inhibitors such as: induction of apoptosis, inhibition of neoplasia, angiogenesis suppression, induction of cell cycle inhibition and ...
Piotr Świątek, Katarzyna Gębczak, Tomasz Gębarowski, Rafal Urniaz   +3 more
openaire   +4 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source