Results 51 to 60 of about 1,096,581 (266)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Борисюк Алла. Психологические особенности профессиональной деятельности врача. Взаимное влияние психики и соматики позволяют говорить о целостном подходе к пациенту.
Борисюк Алла
doaj
Legal Work of the Doctor at the Stage of Primary Health Care
The article deals with the main problems of medical care providing in primary health care, as well as the settlement of legal relations arising in the work of the doctor, and the need for systematization of legal acts which govern the provision of health
N.V. Pasyechko, O.V. Yurchyk
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Medical appointment and its influence on patients' confidence
Introduction Patient’s confidence is very important in patient – doctor communication. It is very vital when we talk about efficient medical care because it can improve this care significently. It is particularly important for people who can not contact
Magdalena Kozimala +3 more
doaj +1 more source
Doctor Watson Architects: AIR Grid Transnational
At a place called Saint Paul-lez-Durance in Southern France there is an enormous construction site where scientists and engineers are building a Tokamak (The word is an abbreviation for toroidal chamber with magnetic coils, it is a device that uses a ...
Watson, V.A.
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Magdalena Waszyk-Nowaczyk,1 Weronika Guzenda,1 Karolina Kamasa,2 Kornel Pawlak,2 Natalia Bałtruszewicz,2 Karolina Artyszuk,2 Artur Białoszewski,3 Piotr Merks4 1Pharmacy Practice Division, Department of Pharmaceutical Technology, Poznan ...
Waszyk-Nowaczyk M +7 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

