Results 61 to 70 of about 905,868 (291)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Doctor Watson Architects: AIR Grid Transnational

open access: yes, 2018
At a place called Saint Paul-lez-Durance in Southern France there is an enormous construction site where scientists and engineers are building a Tokamak (The word is an abbreviation for toroidal chamber with magnetic coils, it is a device that uses a ...
Watson, V.A.
core  

Legal Work of the Doctor at the Stage of Primary Health Care

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2014
The article deals with the main problems of medical care providing in primary health care, as well as the settlement of legal relations arising in the work of the doctor, and the need for systematization of legal acts which govern the provision of health
N.V. Pasyechko, O.V. Yurchyk
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Doctor Photo

open access: yes, 1992
Large colour photo of a male ...
Modbury Hospital
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Doctor Watson Architects: The Architecture School

open access: yes, 2020
This is an animation showing a strategy for an new kind of architecture school.
Watson, V.A.
core  

Medical appointment and its influence on patients' confidence

open access: yesJournal of Education, Health and Sport, 2017
Introduction Patient’s confidence is very important in patient – doctor communication. It is very vital when we talk about efficient medical care because it can improve this care significently. It is particularly important for people who can not contact
Magdalena Kozimala   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Cooperation Between Pharmacists and Physicians – Whether It Was Before and is It Still Ongoing During the Pandemic?

open access: yesJournal of Multidisciplinary Healthcare, 2021
Magdalena Waszyk-Nowaczyk,1 Weronika Guzenda,1 Karolina Kamasa,2 Kornel Pawlak,2 Natalia Bałtruszewicz,2 Karolina Artyszuk,2 Artur Białoszewski,3 Piotr Merks4 1Pharmacy Practice Division, Department of Pharmaceutical Technology, Poznan ...
Waszyk-Nowaczyk M   +7 more
doaj  

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