Results 111 to 120 of about 1,132,182 (312)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Neoliberalization, media, and union resistance : identity struggles in New Zealand education 1984-2014 : a thesis submitted in partial fulfilment of the requirements for the degree in Doctor of Philosophy in Communication and Journalism at Massey University, Wellington, New Zealand [PDF]

open access: yes, 2018
On 13 April 2013, New Zealand’s primary teachers union the New Zealand Educational Institute (NZEI) organized protests across the country, attended by approximately 10,000 members and sympathisers.
Salter, Leon Alick
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Global Discipline Confusion in Management and Business Related Doctorate Programmes [PDF]

open access: yes
Professional doctorate programmes have recently emerged around the globe as an alternative to the more traditional research based doctoral programmes and have expanded rapidly to the point where professional doctorates are now the dominant form of ...
Peter MILLER
core  

Focal Spot, Summer 2001 [PDF]

open access: yes, 2001
https://digitalcommons.wustl.edu/focal_spot_archives/1088/thumbnail ...

core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The Rationale, Challenges and Benefits of Joint Degrees as a New Form of Doctoral Education

open access: yes, 2016
CITATION: Fourie-Malherbe, M., Botha, J. & Stevens, D. 2016. The Rationale, Challenges and Benefits of Joint Degrees as a New Form of Doctoral Education, in M. Fourie-Malherbe, R. Albertyn, C. Aitchison & E. Bitzer. (eds.). Postgraduate Supervision: Future Foci for the Knowledge Society. Stellenbosch: SUN PRESS. 313-333. doi:10.18820/9781928357223/19.
Fourie-Malherbe, Magda   +2 more
openaire   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

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