Results 131 to 140 of about 273,044 (344)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Association of treatment and outcomes of doctor-shopping behavior in patients with hepatocellular carcinoma

open access: yes, 2013
Cheng-I Hsieh,1–3 Kuo-Piao Chung,3 Ming-Chin Yang,3 Tsai-Chung Li4–61Division of Hematology and Oncology, Department of Internal Medicine, Taipei Medical University Hospital, 2Department of Internal Medicine, School of Medicine, College of ...
Chung KP, Hsieh CI, Yang MC, Li TC
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Impact of health care system on socioeconomic inequalities in doctor use [PDF]

open access: yes
This study examines the impact of health system characteristics on social inequities in health care use in Europe, using data from national surveys in 13 European countries.
Engin Yilmaz, Zeynep Or, Florence Jusot
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Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Analytics—doctors of sciences [PDF]

open access: yesJournal of Analytical Chemistry, 2009
openaire   +1 more source

Dr. Dwight J. Ingle receives an honorary Doctor of Science degree from University of Idaho President Donald Theophilus at Commencement

open access: yes, 1962
Dr. Dwight J. Ingle receives an honorary Doctor of Science degree from University of Idaho President Donald Theophilus during the 1962 Commencement ceremony.

core  

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