Results 131 to 140 of about 273,044 (344)
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Cheng-I Hsieh,1–3 Kuo-Piao Chung,3 Ming-Chin Yang,3 Tsai-Chung Li4–61Division of Hematology and Oncology, Department of Internal Medicine, Taipei Medical University Hospital, 2Department of Internal Medicine, School of Medicine, College of ...
Chung KP, Hsieh CI, Yang MC, Li TC
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Impact of health care system on socioeconomic inequalities in doctor use [PDF]
This study examines the impact of health system characteristics on social inequities in health care use in Europe, using data from national surveys in 13 European countries.
Engin Yilmaz, Zeynep Or, Florence Jusot
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In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Dr. Dwight J. Ingle receives an honorary Doctor of Science degree from University of Idaho President Donald Theophilus during the 1962 Commencement ceremony.
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