Results 141 to 150 of about 193,183 (256)

Programa de Pós-Graduação em Geologia - 2005 -- Teses Defendidas - Doutorado - Instituto de Geociências - UFRJ [PDF]

Anuário do Instituto de Geociências, 2005
doaj  

Doctors in Science and Society

Journal of the Royal College of Physicians of London, 1988
openaire   +1 more source

Based on dual perspectives of management and ethics: exploring challenges and governance approaches for new media applications in psychiatric specialty hospitals. [PDF]

Front Digit Health
Wen Q, Shen Y.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Programa de Pós-Graduação em Geografia - Teses Defendidas 2000 - Doutorado - Instituto de Geociências - UFRJ [PDF]

Anuário do Instituto de Geociências, 2000
doaj  

Teaching Personalized Doctor-Patient Communication with AI: PerTRAIN - a Prototype for Interpersonally Responsive Virtual Patients in Medical Education. [PDF]

Perspect Med Educ
Junga A, Hätscher O, Dabel J, Mado G, Ajani A, Pielage L, Kockwelp P, Breil SM, Baur H, Siebenbrock J, Risse B, Grammer T, Marschall B, Back MD.   +13 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

What are the views of cancer care administrators and clinicians in England on the use of a machine learning clinical decision support system (ML-CDSS) to predict patients' risk of hepatic and renal deterioration during chemotherapy? A qualitative study. [PDF]

BMJ Open
Ercia A, Yip M, Reed C, Steventon L, Geoghegan C, Watson M, Kennelly C, Chambers P, Al Moubayed N.   +8 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source