Results 141 to 150 of about 273,044 (344)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
, 1962 Carl P. Clare receives an honorary Doctor of Science degree from University of Idaho President Donald Theophilus during the 1962 Commencement ceremony. Dean Allen S.
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Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Autism’s direct cause? Failure of infant-mother eye contact in a complex adaptive system
, 2011 This paper shows that an experimental hypothesis is plausible and merits testing. In brief the hypothesis is that autism begins with a failure in early learning and that changing the environment of early learning would dramatically change its incidence ...
McDowell, Doctor Maxson J
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
, 2018 Cite: Academy of Science of South Africa (ASSAf), (2018). Quest: Science for South Africa, 14(3). [Online] Available at: http://hdl.handle.net/20.500.11911/103The science of everything Reinhard Hiller explains how our understanding of DNA and the human ...
Academy of Science of South Africa (ASSAf)
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Interpretation and the art of care- Gadamer's hermeneutics and physician wellbeing. [PDF]
Philos Ethics Humanit MedShannon P.
europepmc +1 more source
Earl Thomas Hayes receiving an honorary Doctor of Science degree [2]
, 1971 Earl Thomas Hayes receiving an honorary Doctor of Science degree during the 1971 Commencement ...
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Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source