Results 51 to 60 of about 567,473 (231)

Candida auris Cluster and Mitigation in Burn Center

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Candida auris (CA) is an urgent threat per CDC with rapidly increasing cases across the US. Patient rooms quickly recontaminate after daily cleaning due to skin shedding, CA persistence on environmental surfaces and resistance to surface ...
Erik Stuckart, Casey Walker, Brooke McKie, Jane Echols, Julia Moody, Ken Sands   +5 more
doaj   +1 more source

Birds of Malagos Watershed: A Comparative Sourvey

JPAIR, 2008
The study titled "Birds of Malagos Watershed, Southeastern Philippines" highlights the avifaunal richness of Mindanao, one of the most biodiverse islands in the Philippines.
Geonsyl L. Alviola, Julie B. Otadoy, Bernadette I. del Rosario, Jason Ibañez   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Team-based care in specialist practice: a path to improved physician experience in British Columbia

BMC Health Services Research
Background Specialist physicians in the province of British Columbia commonly work on teams in acute care settings such as operating rooms or inpatient hospital units.
Eric R. Young, Garth Vatkin, Jason Kur, Erin E. Sullivan   +3 more
doaj   +1 more source

The Antiangiogenic Activity of the Pereskia grandifolia (Seven Star Needle) Crude Leaf Extract Using the Chick Embryo Chorioallantoic Membrane (CAM) Assay

Recoletos Multidisciplinary Research Journal
Background: The study focused on the anticancer potential of Pereskia grandifolia, specifically its antiangiogenic properties. Methods: Soxhlet extraction and rotary evaporation yielded a crude leaf extract containing flavonoids, phenols, tannins ...
Aline Abala, Anna Teresa Acuña, Lojsam Daan, Jonessa Pearl Dico, Aleana Dannyze Fontillas, Kevin Christian Dela Cruz   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Doctors for Global Health Statement on Gaza

Social Medicine
We, Doctors for Global Health, write with a broken heart, this letter to publicly condemn the horrific atrocities ongoing in Gaza, which the  United Nations (UN) Special Rapporteur has stated that there are “reasonable grounds” to declare a ...
Doctors for Global Health
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Radiation Attenuation Property of High-Density Polyethylene Doped with Zinc Oxide as an Alternative Gonadal Shield

Recoletos Multidisciplinary Research Journal
Background: The study investigated the radiation attenuation properties of high-density polyethylene doped with zinc oxide as an alternative to the commercially available gonadal shield in different concentrations.
Sofia Van Antonionni Pumar, Roberto Jr. Tagalog, Stephen Andrie Bitoon, Aaliyah Marie Damalerio, Christie Maureese Espinosa, Gleecyl Ann Pros   +5 more
doaj   +1 more source