Results 51 to 60 of about 4,688,083 (288)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Conservation in Kansas

open access: yes, 2008
Report covers Fiscal Year 2007 and 2008, with planned activities listed for Fiscal Year 2009.<br>Continues title: Soil conservation in Kansas which previously was continued by: Conservation in ...
Kansas. State Conservation Commission
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Charge towards green finance ignores risks of nature commodification: Evidence from the UK's climate and nature recovery policy landscape

open access: yesPeople and Nature
The urgent need for up‐scaled finance has become central to the climate and nature recovery discourses worldwide. With most existing investments coming from public sources, closing the financing gap has become the overpowering argument for calling for ...
Julia Martin‐Ortega   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Other title: Publications issued by the Kansas State Conservation Commission and the Division of Conservation, Kansas Department of Agriculture, 2000-2011

open access: yes, 2000
application/pdfA set of four publications gathered from the Kansas Division of Conservation and Kansas State Conservation Commission websites.Make Learning Fun: Conservation Education (2000) Watershed District Handbook (2008) Kansas Conservation District
Kansas. State Conservation Commission.
core   +1 more source

Can methods applied in medicine be used to summarize and disseminate conservation research? [PDF]

open access: yes, 2004
To ensure that the best scientific evidence is available to guide conservation action, effective mechanisms for communicating the results of research are necessary.
Lindenmayer, David B   +15 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Conservation priority mapping [PDF]

open access: yes, 2022
The South Carolina Conservation Bank has been tasked with developing statewide conservation priority maps that will be submitted to the South Carolina General Assembly.
South Carolina Conservation Bank
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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