Results 61 to 70 of about 11,660,074 (399)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Semantic web-based document: editing and browsing in AktiveDoc [PDF]

open access: yes, 2005
This paper presents a tool for supporting sharing and reuse of knowledge in document creation (writing) and use (reading). Semantic Web technologies are used to support the production of ontology based annotations while the document is written. Free text
F. Ciravegna   +5 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

INFORMATION PROVISION OF TOURISM AND ECONOMY IN AZERBAIJAN AND ITS BIBLIOMETRIC ANALYSIS [PDF]

open access: yesGeo Journal of Tourism and Geosites
Tourism is travel for pleasure, and the commercial activity of providing and supporting such travel. Tourism can be domestic (within the traveller's own country) or international, and international tourism has both incoming and outgoing implications on
Sevda KHALAFOVA, Nadir ISMAYILOV
doaj  

Technological development of functionalities with convolutional neural networks for intelligent document management/Desarrollo tecnológico de funcionalidades con redes neuronales convolucionales para una gestión documental inteligente

open access: yesInformador Técnico
In the current highly digitized business landscape, efficient document management is crucial for increasing productivity and optimizing organizational processes.
Erika Marcela Parra-Amaya   +4 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Document Management vs. Knowledge Management [PDF]

open access: yesInformatică economică, 2008
Most large organizations have been investing in various disconnected management technologies during the past few years. Efforts to improve management have been especially noticeable over the last 18-24 months, as organizations try to tame the chaos ...
Sergiu JECAN
doaj  

Optimization Problems of Document Processing Management

open access: yesКібернетика та комп'ютерні технології, 2020
Introduction. The use of various cloud services is becoming an integral part of modern life. At the same time, the owners of such services usually are not going to inform users with the theoretical foundations of the deployment and provision of these ...
Yu.P. Laptin   +2 more
doaj   +1 more source

Enterprise Management Incentives: extending access for academic employees: consultation document [PDF]

open access: yes, 2012
This consultation document seeks comments on proposals to extend access to Enterprise Management Incentives to academics employed by a qualifying company, as announced at Budget ...

core  

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

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