Results 81 to 90 of about 2,566,551 (332)

Advanced analytics as a tool to identify ways to achieve sustainable development [PDF]

, 2013
At this stage of information society is a rational mechanism for the achievement of sustainable development through the use of management information systems.
Zaytseva, K.
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Time Until Proof of Credentials Significantly Decreases With the Use of Blockchain Technology and the Document Management System. [PDF]

Cureus, 2023
Tissier EA, Berglund A, Johnson GJ, Sanzone ZA, Goodbread AP, Parker H, Lucas J, Kashmer D.   +7 more
europepmc   +1 more source

THE PLACE AND IMPORTANCE OF ELECTRONIC DOCUMENTS IN THE FIELD OF STATISTICS AND WAYS OF DEVELOPMENT IN THE SYSTEM OF DOCUMENT MANAGEMENT

, 2022

openalex   +2 more sources

Minimum levels of performance and notices to improve: guidance applying to the 2011/12 academic year [PDF]

, 2010
"This document sets out how the Skills Funding Agency and the Young People’s Learning Agency (YPLA) intend to approach identified provider underperformance in the 2011/12 academic year in respect of: financial health and financial management and ...

core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The Usability of IT Systems in Document Management, Using the Example of the ADPIECare Dorothea Documentation and Nurse Support System. [PDF]

Int J Environ Res Public Health, 2022
Kilańska D, Ogonowska A, Librowska B, Kusiak M, Marczak M, Kozlowski R.   +5 more
europepmc   +1 more source

An integrated information retrieval and document management system [PDF]

This paper describes the requirements and prototype development for an intelligent document management and information retrieval system that will be capable of handling millions of pages of text or other data. Technologies for scanning, Optical Character
Alvarez, J. Fernando, Chen, James, Chen, William, Cheung, Lai-Mei, Clancy, Susan, Coles, L. Stephen, Wong, Alexis   +6 more
core   +1 more source

CBR and MBR techniques: review for an application in the emergencies domain [PDF]

, 2003
The purpose of this document is to provide an in-depth analysis of current reasoning engine practice and the integration strategies of Case Based Reasoning and Model Based Reasoning that will be used in the design and development of the RIMSAT system ...
Merida-Campos, Carlos, Rollón Rico, Emma   +1 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source