Results 51 to 60 of about 201,449 (246)

DOMAIN INDEPENDENT SERVER FOR DOCUMENT MANAGEMENT SYSTEM

Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki, 2019
Domain independent server for document management system is detailed. Server plays a role of basic software which allows to extend functionality of the system. Main objective of suggested server is processing requests from representation layer.
M. V. Sterjanov, I. V. Baidakov
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Using Electronic Systems for Document Management in Economic Entities [PDF]

Informatică economică, 2007
Document workflow and management, be them scanned documents, computer-generated e-documents or complex file formats, are critical elements for the success of an organization.
doaj  

Analysis of Questionnaire Results in the Use of BP and ND in Public Administration

Applied Computer Systems, 2014
The goal of effective public administration is to provide qualitative services to citizens. Due to the increasing use of information and communication technologies (ICT), e-government is one of the possible solutions in achieving this goal. This solution
Survilo Larisa, Buksa Ilze, Gaidukovs Andrejs, Shendryk Vira   +3 more
doaj   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

THE RISKS OF INTRODUCING SYSTEM OF ELECTRONIC DOCUMENT AND WAYS OF OVERCOMING THEM

Advanced Engineering Research, 2014
Work devoted to the study of risks arising at different stages of implementation of system of electronic document. The implementation of electronic document management system is a complex process whose success depends on several factors, therefore it is ...
Mariya Nikolaevna Kulinich, Manana Givievna Komahidze, Lukjyanova Аnastasiya Sergeevna   +2 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Rancang Bangun Secure Document Management System (DMS) Menggunakan Metode Agile-SSDLC

INSERT
Dalam era digital yang semakin maju, pengelolaan dokumen yang dulunya dilakukan secara konvensional (paper based) berubah menggunakan teknologi komputer. Data pada dokumen diolah dan disimpan dalam bentuk digital.
Hermawan Setiawan, Rayhan Ramdhany Hanaputra, Christopher Ralin Anggoman, I Gede Maha Putra, Rheva Anindya Wijayanti, Achmad Luthfan Aufar Hindami   +5 more
doaj   +1 more source