Results 91 to 100 of about 37,588 (256)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
HeritageQuito, recognized as the first UNESCO World Cultural Heritage Site, holds a vast documentary legacy at constant risk of deterioration due to environmental, biological, and aging factors.
Katherine Guacho-Pachacama +10 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
A ALDEIA JESUÍTICA DE CARAPICUIBA NA HISTÓRIA E NO FILME CASINHA PEQUENINA
Travessias, 2014 Before anything, the cinema is a document. As all document, it can be manipulated, to serve as an instrument of manipulation, of social alienation. But before all this is a witness to history, it is a strength in the process of society awareness and a ...
Valter Aparecido Barcala +1 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
The Establishment and Structure of the Iraqi Archive
مجلة جامعة الأنبار للعلوم الإنسانيةAims: This study explores the significance of the Iraqi archive and its academic role in supporting researchers and graduate students. It traces the historical stages of its establishment and growth, beginning with the Iraqi Archives and culminating in ...
amna salah Mohammed, Fahmi Ahmed Farhan
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Big Data & SocietyNew federal research policies support data-driven science by requiring data management planning and data preservation for open access to scientific data and research products.
Amelia Acker +3 more
doaj +1 more source
Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source