Results 31 to 40 of about 37,588 (256)

Tree Snails of Florida, Drymaeus, Orthalicus, Liguus spp. (Gastropoda: Stylommatophora: Bulimulidae)

open access: yesEDIS, 2005
This document provides an overview of Florida's tree snails, focusing on species within the Bulimulidae family. It details their arboreal nature, identification features, and habitats, emphasizing their ecological importance and conservation status. The
Jane E. Deisler
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Crustal rejuvenation stabilised Earth’s first cratons

open access: yesNature Communications, 2021
Why Earth’s crust only started becoming widely preserved in the Eoarchaean, 500 Ma after planetary accretion, is poorly understood. Here, the authors document a shift to juvenile magmatic sources in the early Eoarchaean, linking crustal preservation to ...
Jacob A. Mulder   +5 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Archive preservation in Algeria between legal protection and technical procedures

open access: yesCybrarians Journal, 2006
A study on archival preservation in the State of Algeria. The study begins with a methodological introduction that explains its objectives, questions, and methodology.
Nadjia Gamouh, Fatiha Sharqi
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

A No-Compromises Architecture for Digital Document Preservation [PDF]

open access: yes, 2005
The Multivalent Document Model offers a practical, proven, no-compromises architecture for preserving digital documents of potentially any data format. We have implemented from scratch such complex and currently important formats as PDF and HTML, as well as older formats including scanned paper, UNIX manual pages, TeX DVI, and Apple II AppleWorks word ...
Thomas A. Phelps, Paul B. Watry
openaire   +1 more source

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