Results 61 to 70 of about 4,153,024 (248)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Preservación del patrimonio documental digital en el mundo y en México Preservation of Digital Documentary Heritage in the World and in Mexico

open access: yesInvestigación Bibliotecológica: Archivonomía, Bibliotecología e Información, 2012
Se analiza la evolución de los principales proyectos de preservación documental digital a nivel mundial, destacando sus premisas y elementos más relevantes, así como diversas estrategias que se han desarrollado para su posible preservación.
Juan Voutssás M.
doaj  

Historical Preservation State Grant Fund [PDF]

open access: yes
This document explains the purpose of the Historic Preservation State Grant Fund, which is to support historic preservation projects that benefit local communities through the physical repair and rehabilitation of South Carolina’s historic buildings
South Carolina State Historic Preservation Office
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Historic Preservation League News

open access: yes, 1990
Newsletter of the Dallas Historic Preservation League describing the group's activities, news, and events, as well as other preservation information of interest to ...
Dallas Historic Preservation League
core   +1 more source

Historic Preservation League News

open access: yes, 1994
Newsletter of the Dallas Historic Preservation League describing the group's activities, news, and events, as well as other preservation information of interest to ...
Dallas Historic Preservation League
core   +2 more sources

Revistes electròniques, comunicació científica i biblioteques

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2001
El recent auge de les revistes científiques electròniques va tenir els seus inicis quan les biblioteques van començar a tenir accés a la World Wide Web (WWW) a mitjan dels noranta.
Keefer, Alice
doaj  

International Internet Preservation Consortium Strategic Plan 2016 - 2017

open access: yes, 2016
This document sets forth the mission and goals of the International Internet Preservation Consortium as well as its 2016-2017 strategic ...
International Internet Preservation Consortium
core  

Genre Classification in Automated Ingest and Appraisal Metadata [PDF]

open access: yes, 2006
Metadata creation is a crucial aspect of the ingest of digital materials into digital libraries. Metadata needed to document and manage digital materials are extensive and manual creation of them expensive.
Ross, S   +7 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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